1796570-08-5
1796570-08-5
Chemical Structure
Netakimab
Synonym(s): BCD-085
- CAS No.: 1796570-08-5
- Formula:N/A
- Molecular Weight:(145.74 kDa)
IUPAC Name: ethyl 3-oxobutanoate-4,4,4-d3
SMILES: [Netakimab]
Biological Activity: Netakimab (BCD-085) is a humanized IgG1κ monoclonal anti-IL-17 antibody that binds to and blocks IL-17 and IL-17A activity, including reduction of downstream IL-6 production. Netakimab can be used for the research of moderate-to-severe plaque psoriasis, ankylosing spondylitis, and COVID-19 with cytokine release syndrome[1][2]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Netakimab | 95.00% | Netakimab (BCD-085) is a humanized IgG1κ monoclonal anti-IL-17 antibody that binds to and blocks IL-17 and IL-17A activity, including reduction of downstream IL-6 production. Netakimab can be used for the research of moderate-to-severe plaque psoriasis, ankylosing spondylitis, and COVID-19 with cytokine release syndrome. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). | ||||||||||||||||||||
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References
- [1]. Puig L, et al. Efficacy and Safety of Netakimab, A Novel Anti-IL-17 Monoclonal Antibody, in Patients with Moderate to Severe Plaque Psoriasis. Results of A 54-Week Randomized Double-Blind Placebo-Controlled PLANETA Clinical Trial. Dermatol Ther (Heidelb). 2021;11(4):1319-1332. [Content Brief]
- [2]. Maslennikov R, et al. Interleukin 17 antagonist netakimab is effective and safe in the new coronavirus infection (COVID-19). Eur Cytokine Netw. 2021;32(1):8-14. [Content Brief]
