1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-120966
    NCX 2121 301838-28-8 98%
    NCX 2121 (NO-indomethacin) is an anti-inflammatory agent. NCX 2121 inhibits PaCa-2 cells growth witn an IC50 of 82 μM.
    NCX 2121
  • HY-120975
    2,3-Dinor thromboxane b1 196493-76-2 98%
    2,3-Dinor thromboxane b1 is an urinary metabolite of Thromboxane B2 (HY-113331).
    2,3-Dinor thromboxane b1
  • HY-12100S
    Umeclidinium-d5 bromide 98%
    Umeclidinium-d5 (bromide) is the deuterium labeled Umeclidinium bromide. Umeclidinium bromide is a novel mAChR antagonist. The affinity (Ki) of Umeclidinium bromide for the cloned human M1-M5 mAChRs ranges from 0.05 to 0.16 nM.
    Umeclidinium-d5 bromide
  • HY-121038
    Chamazulene 529-05-5 98.96%
    Chamazulene, a natural compound, is an antioxidant-type inhibitor of leukotriene B4 formation.
    Chamazulene
  • HY-121043
    AA 497 free base 59605-49-1 98%
    AA 497 free base is an adrenergic beta-2 agonist. AA 497 free base is a bronchodilator.
    AA 497 free base
  • HY-121046
    Flunixin 38677-85-9 98%
    Flunixin is a cyclooxygenase (COX) inhibitor with IC50 values of 0.55 and 3.24 μM for COX-1 and COX-2, respectively. Flunixin shows anti-inflammatory effects.
    Flunixin
  • HY-121062
    Betamethasone acibutate 5534-05-4 98%
    Betamethasone acibutate, derives from Betamethasone, is an acetate ester. Betamethasone acibutate is a glucocorticoid.
    Betamethasone acibutate
  • HY-121076
    Berteroin 4430-42-6 99.9%
    Berteroin, a naturally occurring Sulforaphane analog, ia an antimetastatic agent. Berteroin has anti-inflammatory, antitumor and bactericidal effects.
    Berteroin
  • HY-121097
    Diapocynin 29799-22-2 99.0%
    Diapocynin (Dehydrodiacetovanillone), a dimeric derivative of Apocynin, is an orally active NADPH oxidase inhibitor. Diapocynin has anti-inflammatory, neuroprotection and antioxidant activities.
    Diapocynin
  • HY-121103
    Aclantate 39633-62-0 98%
    Aclantate is a nonsteroidal anti-inflammatory drug with anti-inflammatory and analgesic activity. Aclantate is mainly used to relieve various types of pain and reduce inflammatory responses. Aclantate can be used to suppress rheumatoid arthritis and other related diseases.
    Aclantate
  • HY-121124
    Fluindione 957-56-2 98%
    Fluindione is a inhibitor of 5-lipoxygenase with the IC50 of 15 μM. Fluindione has antiinflammatory activity.
    Fluindione
  • HY-121132
    Butibufen 55837-18-8 98.91%
    Butibufen is an orally active non-steroidal compound. Butibufen shows analgesic and antipyretic properties. Butibufen can be used for the research of inflammation.
    Butibufen
  • HY-121154
    Hexachloroparaxylene 68-36-0 98%
    Hexachloroparaxylene could be used in the study of in fascioliasis in swine.
    Hexachloroparaxylene
  • HY-12119B
    GW274150 dihydrochloride 438542-17-7 98%
    GW274150 (dihydrochloride) is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 μM; Kd=40 nM) and rat iNOS (ED50=1.15 μM). GW274150 (dihydrochloride) displays less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 (dihydrochloride) exerts a protective role in an acute model of lung injury inflammation.
    GW274150 dihydrochloride
  • HY-121239
    Lemnalol 82570-34-1 98%
    Lemnalol is a potent agent for neuropathic pain. Lemnalol possesses potent anti-inflammatory, analgesic and anti-tumor activities. Lemnalol has the capacity to attenuate hyperalgesia and allodynia by modulation of neuroinflammatory processes in neuropathy. Lemnalol modulates LPS-induced alterations of left atrial (LA) calcium homeostasis and blocks the NF-κB pathways, which may contribute to the attenuation of lipopolysaccharide (LPS)-induced arrhythmogenesis and neuropathic pain. Lemnalolis a ylangene-type sesquiterpenoid compound, isolated from Lemnalia cervicorni.
    Lemnalol
  • HY-121272
    Difloxacin 98106-17-3 98%
    Difloxacin is an antimicrobial agent.
    Difloxacin
  • HY-121278
    Benzotript 39544-74-6 98%
    Benzotript (Benzotriptum) is a cholecystokinin-receptor (CCK) and gastrin receptor antagonist. Benzotript shows antiproliferative effects in human colon carcinoma cell lines.
    Benzotript
  • HY-121293
    CP-944629 668990-94-1 98%
    CP-944629 (Compound 20) is an inhibitor of p38 alpha kinase with an IC50 of 3.2. CP-944629 can be studied in research for chronic inflammation diseases.
    CP-944629
  • HY-121347
    Enterocin 59678-46-5 98%
    Enterocin, an antibiotic, has static activities against gram-positive and gram-negative bacteria and no activity against fungi and yeast.
    Enterocin
  • HY-121351
    Inokosterone 15130-85-5 98%
    Inokosterone is a potential agent target of estrogen receptor 1 in rheumatoid arthritis patients.
    Inokosterone
Cat. No. Product Name / Synonyms Application Reactivity