2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-126564
    Ebelactone A 76808-16-7 98.28%
    Ebelactone A is a mycolic acid β-lactone, which exhibits inhibitory activity for esterase, lipase, fMet aminopeptidase (fMet AP) and PNBase, with IC50s of 56, 3, 8 and 7.5 μM, respectively. Ebelactone A inhibits cutinase, exhibits plants protective potency against Erysiphe graminis.
    Ebelactone A
  • HY-126609
    Emorfazone 38957-41-4 98%
    Emorfazone (Pentoil) is a non-steroidal anti-inflammatory drug with oral activity. Emorfazone can significantly inhibit the release of bradykinin-like substances and kininogen. Emorfazone has anti-inflammatory and analgesic activity.
    Emorfazone
  • HY-126696
    Altromycin D 128461-01-8 98%
    Altromycin D is a Gram-positive antibiotic.
    Altromycin D
  • HY-126715
    Pimelautide 78512-63-7 98%
    Pimelautide (RP 44102), a desmuramyl peptidolipid, is an adjuvant. Pimelautide shows a LD50 of 410 mg/kg (i.v, mouse).
    Pimelautide
  • HY-126716
    Leukotriene C4 methyl ester 73958-10-8 98%
    Leukotriene C4 methyl ester is a methyl ester of leukotriene C4. Leukotriene C4 methyl ester can be used for the research of psoriasis.
    Leukotriene C4 methyl ester
  • HY-126722
    Lipoxin A4 methyl ester 97643-35-1 98%
    Lipoxin A4 methyl ester is a stable synthetic analog of lipoxin with anti-inflammatory properties that can be extracted from arachidonic acid.
    Lipoxin A4 methyl ester
  • HY-126754
    Archangelicin 2607-56-9 98%
    Archangelicin is an inhibitor for cAMP-phosphodiesterase (cAMP-PDE) with IC50 >400 μM. Archangelicin inhibits nuclear factor of activated T cell (NFAT) with IC50 of 9 μM. Archangelicin exhibits antitumor and anti-inflammatory.
    Archangelicin
  • HY-126787
    17-Hydroxyventuricidin A 113204-43-6 98%
    17-Hydroxyventuricidin A (YP-02259L-C) is an antimicrobial compound.17-Hydroxyventuricidin A inhibits the growth of the two tested filamentous fungi (Verticillium dahlia and Fusarium sp.) and of Candida tropicalis R2 CIP203.
    17-Hydroxyventuricidin A
  • HY-126800
    Glycotriosyl glutamine 83235-86-3 98%
    Glycotriosyl glutamine is a synthetic analogue of the Glycopeptide. Glycotriosyl glutamine induces focal glomerulonephritis (FGN) and the appearance of myeloid bodies in the epithelial cells of the podocytes in rats with nephritogenic activity.
    Glycotriosyl glutamine
  • HY-126836
    L-685487 132055-38-0 98%
    L-685487 is a 13-desmethyl derivative of FK506 (HY-13756). L-685487 is promising for research of immunomodulators.
    L-685487
  • HY-126852
    4-Hydroxy Atorvastatin lactone 163217-70-7 98%
    4-Hydroxy Atorvastatin lactone is a metabolite of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.
    4-Hydroxy Atorvastatin lactone
  • HY-126883
    Tr-PEG4-OH 125274-16-0
    Tr-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
    Tr-PEG4-OH
  • HY-126898
    5-LO/mPGES1-IN-1 1492060-44-2 99.00%
    5-LO/mPGES1-IN-1 (Compound 16) is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LO). IC50 values are 0.3 and 0.4 μM, respectively. 5-LO/mPGES1-IN-1 has anti-inflammatory activity.
    5-LO/mPGES1-IN-1
  • HY-126956
    Porphyra 334 70579-26-9 98%
    Porphyra 334 is a carnosine-like amino acid and a natural photoprotective agent and antioxidant. Porphyra-334 exerts its photoprotective effects by scavenging ROS, inhibiting the expression and activity of MMP-1/8, and promoting the synthesis of collagen and elastin. Porphyra 334 effectively inhibits linoleic acid oxidation induced by alkyl radicals (AAPH) and singlet oxygen. Porphyra 334 has anti-obesity potential by inhibiting the expression of PPARγ2 and C/EBPα. Porphyra 334 protects cells against UV-induced DNA damage and apoptosis by inhibiting the activation of caspase-3.
    Porphyra 334
  • HY-126980
    AMG-126737 224054-76-6 98%
    AMG-126737 is an orally active and highly selective human mast cell tryptase inhibitor with a Ki of 90 nM. AMG-126737 suppresses early/late-phase bronchoconstriction in sheep models. AMG-126737 is promising for research of asthma and allergic diseases.
    AMG-126737
  • HY-127003
    Neoambrosin 18446-70-3 98%
    Neoambrosin is a sesquiterpene lactone. Neoambrosin acts as a partial agonist of PPARγ and TRPA1 receptors, with no carbonic anhydrase inhibitory activity. Neoambrosin can be used in research on hypoglycemia, analgesia, anti-inflammation and anticancer effects.
    Neoambrosin
  • HY-127038
    Diflumidone sodium 22737-01-5 98%
    Diflumidone sodium is a non-steroidal antiinflammatory agent.
    Diflumidone sodium
  • HY-127040
    Talastine hydrochloride 16188-76-4 98%
    Talastine hydrochloride is an antihistamine with antiallergic activity. Talastine hydrochloride is used to relieve allergic symptoms. Talastine hydrochloride may cause adverse reactions such as rash, indicating differences in individual sensitivity. Talastine hydrochloride is considered a potential option for inhibiting allergic reactions.
    Talastine hydrochloride
  • HY-127067
    Yuanhuadin 76402-66-9 98%
    Yuanhuadin, extracted from Genkwa Flos Daphne genkwa, has antitumor activity through inhibiting Akt/mTOR and EGFR pathways, induce cell-cycle arrest and abortion.
    Yuanhuadin
  • HY-127115
    Sulukast 98116-53-1 98%
    Sulukast (LY 170680) is a selective leukotriene D4 (LTD4) antagonist. Sulukast exerts an effective antagonistic effect on bronchoconstriction induced by LTD4. Sulukast can be used in the research of diseases such as asthma.
    Sulukast
Cat. No. Product Name / Synonyms Application Reactivity