Neoambrosin
Neoambrosin is a sesquiterpene lactone. Neoambrosin acts as a partial agonist of PPARγ and TRPA1 receptors, with no carbonic anhydrase inhibitory activity. Neoambrosin can be used in research on hypoglycemia, analgesia, anti-inflammation and anticancer effects.
For research use only. We do not sell to patients.
- CAS No.: 18446-70-3
- Formula: C15H18O3
- Molecular Weight:246.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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TRPA1 |
PPARγ |
Neoambrosin (0.1-50 μM; 24 h) reduces viability of COS-7 cells at 30 μM and 50 μM after 24 h of treatment, with no significant effect at lower concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:COS-7 monkey kidney fibroblast-like cells
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Concentration:0.1 μM; 1 μM; 3 μM; 10 μM; 30 μM; 50 μM
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Incubation Time:24 h
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Result:Reduced cell viability by approximately 50% relative to vehicle at 30 μM.
Reduced cell viability by approximately 70% relative to vehicle at 50 μM.
Did not significantly affect cell viability relative to vehicle at 0.1, 1, 3, and 10 μM.
Chemical Information
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CAS No. 18446-70-3
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Molecular Weight 246.31
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Formula C15H18O3
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SMILES
C[C@]12[C@]3([C@](C(=C)C(=O)O3)(CC[C@H](C)C1=CCC2=O)[H])[H]
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Neoambrosin Related Classifications
HY-127003 Related Classifications
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