Hypoglycemia

3,3-Azo-1-butanol is an orally active hypoglycemic agent. 3,3-Azo-1-butanol increases liver weight and induces fat infiltration.

(Asp28)-Glucagon (1-29) (human, rat, porcine) is a glucagon analog and a GCGR agonist, with the Asn at position 28 replaced by Asp. (Asp28)-Glucagon (1-29) (human, rat, porcine) activates GCGR-mediated cAMP signaling, with EC₅₀ values of 0.067 nM and 0.09 nM, respectively, and an EC₅₀ of 7.99 nM for GLP-1R. (Asp28)-Glucagon (1-29) (human, rat, porcine) is useful for studies on glucagon receptor signaling, carbohydrate metabolism, and hypoglycemia.

Cyclocarioside K is a triterpene glycoside compound that can be naturally extracted from the dried leaves of Cyclocarya paliurus (Batal.) Iljinsk (Chinese wingnut) from Bozhou, Anhui, China. The leaves of this plant are traditionally used to lower blood sugar and blood pressure.

Glucagon receptor antagonist-11 (Compound 14) is a glucagon receptor antagonist with a pIC₅₀ of 6.677. Glucagon receptor antagonist-10 can be used in studies of glucose homeostasis.

Glucagon receptor antagonist-10 (Compound 11) is a glucagon receptor antagonist with a pIC₅₀ of 7.154. Glucagon receptor antagonist-10 can be used in studies of glucose homeostasis.