Hypoglycemia

Hypoglycemia is a condition characterized by abnormally low blood glucose levels, typically below 70 mg/dL (3.9 mmol/L), and is commonly observed in patients with fulminant hepatic failure (FHF). It results from impaired glucose production and regulation, leading to symptoms such as headache, fatigue, confusion, sweating, tremors, and in severe cases, loss of consciousness or seizures. Diagnosis is based on Whipple's triad: documented hypoglycemia, associated clinical symptoms, and relief of symptoms upon glucose normalization. As glucose is the primary energy source for the body, its deficiency disrupts normal metabolic function, requiring prompt identification and management to prevent serious complications.

References:

[1]. Hypoglycemia. sciencedirect.

Hypoglycemia (4):

Targets:	GCGR (2) TRP Channel (1)

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-180446

Glucagon receptor antagonist-11	152121-19-2
Glucagon receptor antagonist-11 (Compound 14) is a glucagon receptor antagonist with a pIC₅₀ of 6.677. Glucagon receptor antagonist-10 can be used in studies of glucose homeostasis.

HY-180445

Glucagon receptor antagonist-10	152121-54-5
Glucagon receptor antagonist-10 (Compound 11) is a glucagon receptor antagonist with a pIC₅₀ of 7.154. Glucagon receptor antagonist-10 can be used in studies of glucose homeostasis.

HY-W093416

3,3-Azo-1-butanol	25055-82-7
3,3-Azo-1-butanol is an orally active hypoglycemic agent. 3,3-Azo-1-butanol increases liver weight and induces fat infiltration.

HY-N17200

Cyclocarioside K	2093058-16-1
Cyclocarioside K is a triterpene glycoside compound that can be naturally extracted from the dried leaves of Cyclocarya paliurus (Batal.) Iljinsk (Chinese wingnut) from Bozhou, Anhui, China. The leaves of this plant are traditionally used to lower blood sugar and blood pressure.

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