Ebelactone A 

Ebelactone A is a mycolic acid β-lactone, which exhibits inhibitory activity for esterase, lipase, fMet aminopeptidase (fMet AP) and PNBase, with IC₅₀s of 56, 3, 8 and 7.5 μM, respectively^[1]. Ebelactone A inhibits cutinase, exhibits plants protective potency against Erysiphe graminis^[2].

56 μM (esterase), 3 μM (lipase), 8 μM (fMet AP), 7.5 μM (PNBase)

Ebelactone A (0.1-1 mM) inhibits germination, AGT formation and sporulating colony formation on barley leafs^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

338.48

C₂₀H₃₄O₄

76808-16-7

CC[C@@H](C)[C@@H](O)[C@H](C)C([C@H](C)/C=C(C)/C[C@@H]([C@@]1([H])[C@@H](C(O1)=O)C)C)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Umezawa H, et al., Ebelactone, an inhibitor of esterase, produced by actinomycetes. J Antibiot (Tokyo). 1980 Dec;33(12):1594-6.  [Content Brief]

  [2]. Francis S A, et al., The role of cutinase in germling development and infection byErysiphe graminisf. sp. hordei[J]. Physiological and Molecular Plant Pathology, 1996, 49(3): 201-211.