2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Nombre del producto No. CAS Pureza Estructura química
  • HY-15656R
    Ceritinib (Standard) 1032900-25-6 99.72%
    Ceritinib (Standard) is the analytical standard of Ceritinib (HY-15656). This product is intended for research and analytical applications. Ceritinib is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib shows great antitumor potency.
    Ceritinib (Standard)
  • HY-156711
    Ternatumoside II 1473419-87-2 98%
    Ternatumoside II is a flavonoid glycoside that can be isolated from R. crenulata. Ternatumoside II can stimulate IFN-γ expression. Ternatumoside II has radical-scavenging activities (IC50s: 260.5 μM and 320.2 μM for DPPH and ABTS).
    Ternatumoside II
  • HY-15701R
    Leukadherin-1 (Standard) 344897-95-6
    Leukadherin-1 (Standard) is the analytical standard of Leukadherin-1. This product is intended for research and analytical applications. Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18, increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC50 of 4 μM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling.
    Leukadherin-1 (Standard)
  • HY-157040
    MAGL-IN-9 3017151-74-2 98%
    MAGL-IN-9 (compound 16) is a selective and reversible MAGL inhibitor with IC50 2.7 nM.
    MAGL-IN-9
  • HY-157042
    MAGL-IN-11 3017151-84-4 98%
    MAGL-IN-11 (compound 29) is a selective and reversible MAGL inhibitor. MAGL-IN-11 has the potential to study inflammation, cancer and antioxidants.
    MAGL-IN-11
  • HY-157121
    JAK-IN-34 2068766-90-3 98%
    JAK-IN-34 (compound 11n) is a potent against of JAKs with IC50 values of 0.40, 0.83, 2.10, 1.95 nM target JAK1, JAK2, JAK3, TYK2, respectively. JAK-IN-34 reduces joint swelling with good safety.
    JAK-IN-34
  • HY-157171
    Ac-YR-NH2 126530-17-4 98%
    Ac-YR-NH2 is a small molecule modulator of MHC class II antigen presentation. Ac-YR-NH2 can influence peptide binding by MHC II to influence immune response.
    Ac-YR-NH2
  • HY-157174
    Mannosamine–desthiobiotin adduct 98%
    Mannosamine-desthiobiotin adduct (compound MDTBA) is a carrier immunogenicity-reducing hapten that reduces the immunogenicity of protein carriers upon conjugation to available free amines on the carrier protein surface. Conjugation of Mannosamine-desthiobiotin adduct to hsIgG significantly (>1-fold) reduced the immunogenicity of hsIgG. Mannosamine-desthiobiotin adduct can be used in antigen design research.
    Mannosamine–desthiobiotin adduct
  • HY-157193
    Diacylglyceride 73566-74-2 98%
    Diacylglyceride, a natural scaffolding lipid, is a hapten that binds to CD1b. Diacylglyceride can be combined with carrier proteins and used in the design of antigens.
    Diacylglyceride
  • HY-157201
    ZEo 98%
    Zeo is a hapten of zearalenone with longer linkers and with alternative tethering sites have been designed for immunizing and assay conjugate preparation.
    ZEo
  • HY-157202
    Zeoh 98%
    Zeoh, an immunizing and heterologous hapten, contains one unprotected OH group at a distal position.
    Zeoh
  • HY-157218
    PPm 2101951-47-5 98%
    PPm, a derivative of penthiopyrad and hapten, is a representative member of the succinate dehydrogenase inhibitors group of fungicides.
    PPm
  • HY-157235
    AC Antibody affinity resin 98%
    AC Antibody affinity resin is AC commonly used packing. AC Antibody affinity resin has highly cross-linked agarose matrix with 85 μm of average particle size. AC Antibody affinity resin has alkali-resistant protein A derivative (E. coli) ligand. AC Antibody affinity resin can be used for antibody affinity chromatography.
    AC Antibody affinity resin
  • HY-15724R
    Vercirnon (Standard) 698394-73-9 98%
    Vercirnon (Standard) is the analytical standard of Vercirnon. This product is intended for research and analytical applications. Vercirnon (GSK1605786A) is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 μM for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively.
    Vercirnon (Standard)
  • HY-157258
    Trimethoprim pentanoic acid 78025-89-5 98%
    Trimethoprim pentanoic acid is hapten. Trimethoprim pentanoic acid shows IC50 of 0.15 ng/mL when exposed diaminopyrimidine moiety to the immune system.
    Trimethoprim pentanoic acid
  • HY-157280
    AdCaPy 307320-40-7 98%
    AdCaPy is an MHC II antigen loading catalyst that accelerates the loading of peptide antigens by MHC II. AdCaPy is a useful molecular tool for enhancing immune responses.
    AdCaPy
  • HY-157282
    Photolumazine I 29161-67-9 98%
    Photolumazine I(PLI) is a vitamin B-based hapten.Photolumazine Icanactivates Mucosal-associated Invariant T clones.
    Photolumazine I
  • HY-157287
    (S)-Phe-A110/B319 98%
    (S)-Phe-A110/B319 is a selective binde that has 20-fold higher affinity towards the H1047R mutant of p110α in the p110α/p85α PI3K complex.
    (S)-Phe-A110/B319
  • HY-157333
    CYP51-IN-15 3034186-60-9 98%
    CYP51-IN-15 (9B) is a BBB penetrated Naegleria fowleri-specific CYP51 inhibitor, with an EC50 of 1.5 μM.
    CYP51-IN-15
  • HY-157472
    ACT-1014-6470 2363082-87-3 98%
    ACT-1014-6470 is an orally active, potent, reversible, and selective C5aR1 antagonist. ACT-1014-6470 demonstrates potent inhibition of C5aR1 activation. ACT-1014-6470 can be used in the research of inflammatory diseases.
    ACT-1014-6470
Cat. No. Nombre del producto / Synonyms Application Reactivity