JAK-IN-34
JAK-IN-34 (compound 11n) is a potent against of JAKs with IC50 values of 0.40, 0.83, 2.10, 1.95 nM target JAK1, JAK2, JAK3, TYK2, respectively. JAK-IN-34 reduces joint swelling with good safety.
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- CAS No.: 2068766-90-3
- Formule: C27H26N6O
- Masse moléculaire:450.53
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
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JAK1 0.40 nM (IC50) |
JAK2 0.83 nM (IC50) |
JAK3 2.10 nM (IC50) |
Tyk2 1.95 nM (IC50) |
Chemical Information
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CAS No. 2068766-90-3
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Masse moléculaire 450.53
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Formule C27H26N6O
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SMILES
N#CCOC1=CC=C(C2=CC=CC3=C2N=C(NC4=CC=CC(N5CCN(CC5)C)=C4)N=C3)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)