2068766-90-3
2068766-90-3
Chemical Structure
JAK-IN-34
- CAS No.: 2068766-90-3
- Formula:C27H26N6O
- Molecular Weight:450.53
InChIKey: UQSABQRSLNYCRM-UHFFFAOYSA-N
SMILES: N#CCOC1=CC=C(C2=CC=CC3=C2N=C(NC4=CC=CC(N5CCN(CC5)C)=C4)N=C3)C=C1
Biological Activity:
JAK-IN-34 (compound 11n) is a potent against of JAKs with IC50 values of 0.40, 0.83, 2.10, 1.95 nM target JAK1, JAK2, JAK3, TYK2, respectively. JAK-IN-34 reduces joint swelling with good safety[1].
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JAK-IN-34 | JAK-IN-34 (compound 11n) is a potent against of JAKs with IC50 values of 0.40, 0.83, 2.10, 1.95 nM target JAK1, JAK2, JAK3, TYK2, respectively. JAK-IN-34 reduces joint swelling with good safety. |
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References
Keywords
