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Cat. No.: HY-157333

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CYP51-IN-15

CYP51-IN-15 (9B) is a BBB penetrated Naegleria fowleri-specific CYP51 inhibitor, with an EC₅₀ of 1.5 μM.

For research use only. We do not sell to patients.

CAS No.: 3034186-60-9
Formula: C₁₉H₁₅Cl₂F₃N₂O
Molecular Weight:415.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

CYP51-IN-15 Chemical Structure

CAS No.: 3034186-60-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

CYP51-IN-15 (9B) is a BBB penetrated Naegleria fowleri-specific CYP51 inhibitor, with an EC₅₀ of 1.5 μM^[1].

All Parasite Isoforms :

All Cytochrome P450 Isoforms :

Chemical Information

CAS No. 3034186-60-9
Molecular Weight 415.24
Formula C₁₉H₁₅Cl₂F₃N₂O
SMILES

FC(C1=CC(CO[C@@H](C2=CC=C(Cl)C=C2Cl)CN3C=CN=C3)=CC=C1)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Vandna Sharma, et al. Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors. J Med Chem. 2023 Dec 12. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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CYP51-IN-15

All Parasite Isoforms

All Cytochrome P450 Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CYP51-IN-15 Related Classifications

HY-157333 Related Classifications

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