1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1610R
    Sodium citrate dihydrate (Standard)
    Inhibitor
    Sodium citrate (dihydrate) (Standard) is the analytical standard of Sodium citrate (dihydrate). This product is intended for research and analytical applications. Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer.
    Sodium citrate dihydrate (Standard)
  • HY-147805
    SARS-CoV-2 3CLpro-IN-4
    Inhibitor
    SARS-CoV-2 3CLpro-IN-4 (Compound 5g) is a SARS CoV-2 3CLpro inhibitor with antiviral, antibacterial and antifungal activities.
    SARS-CoV-2 3CLpro-IN-4
  • HY-N14959
    Deacetylravidomycin N-oxide
    Inhibitor
    Deacetylravidomycin N-oxide is an antibiotic that can be produced by Streptomyces ravidus S50905. Deacetylravidomycin N-oxide is active against Gram-positive bacteria but inactive against Gram-negative bacteria. Deacetylravidomycin N-oxide has antitumor activity against P388 leukemia and methamphetamine A fibrosarcoma.
    Deacetylravidomycin N-oxide
  • HY-W010611R
    3,3-Dimethylacrylic acid (Standard)
    Inhibitor
    3,3-Dimethylacrylic acid (Standard) (3-Methylcrotonic acid (Standard)) is the analytical standard of 3,3-Dimethylacrylic acid (HY-W010611). This product is intended for research and analytical applications.3,3-Dimethylacrylic acid is an active small molecule, that can be used as drug intermediate.
    3,3-Dimethylacrylic acid (Standard)
  • HY-151550
    Mtb-cyt-bd oxidase-IN-3
    Inhibitor
    Mtb-cyt-bd oxidase-IN-3 (compound 1u) is a Mycobacterium tuberculosis cytochrome bd oxidase (Mtb cyt-bd oxidase) inhibitor with an IC50 value of 0.36 μM. Mtb-cyt-bd oxidase-IN-3 inhibits the growth of Mycobacterium tuberculosis (MIC=32 μM). Mtb-cyt-bd oxidase-IN-3 can be used in tuberculosis research.
    Mtb-cyt-bd oxidase-IN-3
  • HY-179529
    EGFR/InhA-IN-1
    Inhibitor
    EGFR/InhA-IN-1 (Compound 15) is an inhibitor of the anti-cancer target EGFR tyrosine kinase (1M17) (Ki = 0.05 μM) and the anti-tuberculosis target InhA enzyme (1OUZ) (Ki = 0.02 μM). EGFR/InhA-IN-1 exhibits anti-proliferative activity against A549 cells, with an IC50 of 10.38 μM. EGFR/InhA-IN-1 has inhibitory activity against Mycobacterium tuberculosis H37Rv, with a MIC of 6.25 μM. EGFR/InhA-IN-1 can be used for research on non-small cell lung cancer and Mycobacterium tuberculosis infection.
    EGFR/InhA-IN-1
  • HY-P11467
    Gy-CATH
    Inhibitor
    Gy-CATH is an anionic antimicrobial peptide. Gy-CATH activates MAPK and NF-κB signaling pathways (elevated levels of phospho-ERK, -p38, -JNK, -p65, and -IκBα). Gy-CATH upregulates the expression levels of three physiological anticoagulant pathways. Gy-CATH inhibits ADP-, Collagen-, and PMA-induced platelet aggregation. Gy-CATH has no direct antimicrobial activity, but shows significant preventive abilities against mice infected with Staphylococcus aureus, Escherichia coli, and Methicillin (HY-121544)-resistant Staphylococcus aureus. Gy-CATH exhibits potent immunomodulatory activity, enhancing macrophage-and neutrophil-mediated bactericidal functions. Gy-CATH significantly reduces the extent of pulmonary fibrin deposition and prevents thrombosis in mice.
    Gy-CATH
  • HY-163481
    Antibiofilm agent-6
    Inhibitor
    Antibiofilm agent-6 (Compound 26c) is a quorum sensing inhibitor with strong antibiofilm effects that can inhibit the fluorescence intensity of PAO1-lasB-gfp and PAO1-pqsA-gfp in a concentration-dependent manner. Antibiofilm agent-6 can inhibit the production of pyocyanin and rhamnolipid. Antibiofilm agent-6 aids helps ciprofloxacin (HY-B0356) effectively eliminate the living bacteria in a mouse model infected with P. aeruginosa PAO1.
    Antibiofilm agent-6
  • HY-148294
    Monogalactosyl diglyceride
    Inhibitor
    Monogalactosyl diglyceride is a antimicrobial. Monogalactosyl diglyceride has antibacterial activity and antifungal activity in vitro.
    Monogalactosyl diglyceride
  • HY-139863
    Antibacterial agent 62
    Inhibitor
    Antibacterial agent 62 is a novel redox cycling antituberculosis chemotype with potent bactericidal activity against growing and nutrient-starved phenotypically drug-resistant nongrowing bacteria.
    Antibacterial agent 62
  • HY-P10603
    SP1
    Inhibitor
    SP1 is an α-peptide encoded by the mating pheromone MFα1 gene in Candida albicans, which can induce cell growth arrest at the mating type locus MTLa in Candida albicans. SP1 can be used in the study of the prevention and treatment of Candida albicans infection.
    SP1
  • HY-N1377R
    Nevadensin (Standard)
    Inhibitor
    Nevadensin (Standard) (Lysionotin (Standard)) is the analytical standard of Nevadensin (HY-N1377). This product is intended for research and analytical applications. Nevadensin, a natural flavonoid, is a selective human carboxylesterase 1 (hCE1) inhibitor with an IC50 of 2.64 μM. Nevadensin is more selective for hCE1 than hCE2 (IC50 of 132.8 μM). Nevadensin can induce apoptosis and DNA damage in cancer cells. Nevadensin has a variety of pharmacological effects such as anti-inflammatory, anti-tumour, anti-hypertensive, anti-tubercular, antitussive, antioxidant and anti-microbial activities.
    Nevadensin (Standard)
  • HY-160653
    JPL
    Inhibitor
    JPL is a InhA-cofactor-ligand 3FNG inhibitor, and can be used for study of tuberculosis.
    JPL
  • HY-P5924A
    D-K6L9
    Inhibitor
    D-K6L9 shows antimicrobial and antibiofilm activities against P. aeruginosa from cystic fibrosis patients. D-K6L9 is stable and resistant to degradation by cystic fibrosis sputum proteases and will not induce bacterial resistance .
    D-K6L9
  • HY-B1236A
    Sulfacarbamide sodium
    Inhibitor
    Sulfacarbamide (Sulfanilylurea, Urosulfan) sodium is a class of sulfonamides with an antimicrobial activity. Sulfacarbamide sodium can be used for the study of diabetes.
    Sulfacarbamide sodium
  • HY-159565
    VEGFR-2/InhA-IN-1
    Inhibitor
    VEGFR-2/InhA-IN-1 is a pyrazole-based dual inhibitor of InhA-VEGFR with anti-tuberculosis and anti-angiogenic activities. VEGFR-2/InhA-IN-1 has good antibacterial activity against Mycobacterium tuberculosis H37Rv strain (MIC=6.25 μg/mL) and significantly inhibits VEGFR-2 (IC50=15.27 nM).
    VEGFR-2/InhA-IN-1
  • HY-149679
    PROTAC eDHFR Degrader-2
    Inhibitor
    PROTAC eDHFR Degrader-2 (compound 7b) is a potent degrader targeting Escherichia coli dihydrofolate reductase (eDHFR), enabling robust degradation of eDHFR-tagged proteins.
    PROTAC eDHFR Degrader-2
  • HY-W004282S2
    Undecanoic acid-d2
    Inhibitor
    Undecanoic acid-d2 (Undecanoate-d2) is the deuterium labeled Undecanoic acid (HY-W004282). Undecanoic acid is a monocarboxylic acid with antifungal property. Undecanoic acid inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum.
    Undecanoic acid-d<sub>2</sub>
  • HY-113627A
    Undecylprodigiosin hydrochloride
    Inhibitor
    Undecylprodigiosin hydrochloride, a member of the family of prodiginines, is a potent antibiotic. Undecylprodigiosin hydrochloride can selectively induce apoptosis in human breast carcinoma cells independent of p53. Undecylprodigiosin hydrochloride shows immunosuppressive, anticancer properties and antimicrobial activities.
    Undecylprodigiosin hydrochloride
  • HY-P11657
    GN-2 peptoid
    Inhibitor
    GN-2 peptoid is a 9-mer cationic amphipathic peptoid and bactericidal agent with an overall net charge of +4, broad-spectrum antimicrobial activity, and low hemolytic and cytotoxic activity against mammalian cells. GN-2 peptoid exerts bactericidal action against Escherichia coli in a concentration-dependent manner. GN-2 peptoid exhibits antimicrobial activity against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli, Pseudomonas aeruginosa strains. GN-2 peptoid shows low toxicity against human red blood cells and HeLa cells. GN-2 peptoid maintains antimicrobial activity in the presence of 50% human blood plasma. GN-2 peptoid can be used for the research of bacterial infections.
    GN-2 peptoid
Cat. No. Product Name / Synonyms Application Reactivity