2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-144100
    β-Lactamase-IN-7
    		Inhibitor
    β-Lactamase-IN-7 (compound 14) is a potent VIM-Type metallo-β-lactamase inhibitor, with Kis of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively. β-Lactamase-IN-7 can effectively inhibit Klebsiella pneumoniae.
    β-Lactamase-IN-7
  • HY-122292
    Celastramycin A
    		Inhibitor
    Celastramycin A is an antibiotic isolated from Streptomyces MaB-QuH-8, which exhibits antimicrobial activity against series of gram-negative bacteria and mycobacteria, with MICs between 0.05-3.1 μg/ml. Celastramycin A exhibits immunosuppressing efficacy in ex vivo Drosophila through immune deficiency pathway (IC50 of 0.008 μg/ml), inhibits the immunoresponse in human innate immunity through TNF-α signaling, inhibits IL-8 production in HUEVCs with IC50 of 0.06 μg/ml.
    Celastramycin A
  • HY-150330
    DNA ligase-IN-1
    		Inhibitor
    DNA ligase-IN-1 (Compound 1) is an inhibitor of bacterial NAD+-dependent DNA ligase (LigA). DNA ligase-IN-1 effectively inhibits the growth of Staphylococcus aureus in vitro.
    DNA ligase-IN-1
  • HY-P5637
    Tur1A
    		Inhibitor
    Tur1A is an antimicrobial peptide derived from bottlenose dolphins Tursiops truncates. Tur1A inhibits bacterial protein synthesis by binding to ribosomes and blocking the transition from the initiation stage to the extension stage.
    Tur1A
  • HY-N18009
    1-Hydroxy-3,5-dimethoxyxanthone
    		Inhibitor
    1-Hydroxy-3,5-dimethoxyxanthone is a xanthone and Antibacterial agent. 1-Hydroxy-3,5-dimethoxyxanthone can be isolated from Lomatogonium rotatum. 1-Hydroxy-3,5-dimethoxyxanthone inhibits the growth of Pseudomonas aeruginosa ATCC27853 and Escherichia coli ATCC25923 with an MIC of 640 μg/mL. 1-Hydroxy-3,5-dimethoxyxanthone exhibits anticancer activity against cervical cancer, breast cancer, melanoma, liver cancer, and gastric cancer.
    1-Hydroxy-3,5-dimethoxyxanthone
  • HY-P11131
    hLF (28-34)
    		Inhibitor
    hLF (28-34) (Human lactoferrin (28-34)) is a loop region of human lactoferrin (hLF) that is essential for the high-affinity binding of LPS. hLF (28-34) is a key site responsible for its high-affinity binding to E. coli 055B5 lipopolysaccharide. hLF (28-34) can be used for antibacterial research.
    hLF (28-34)
  • HY-145986
    CBR-6672
    		Inhibitor
    CBR-6672 is a mycobacterium tuberculosis (Mtb) type II NADH dehydrogenase inhibitor, with the MIC of 0.14 μM against Mtb.
    CBR-6672
  • HY-P3511
    Friulimicin D
    		Inhibitor
    Friulimicin D, a lipopeptide antibiotic, like Friulimicin B, is isolated from the actinomycete Actinoplanes friuliensis.
    Friulimicin D
  • HY-P10604
    SP2
    		Inhibitor
    SP2 is a 14-amino acid long active peptide that can induce growth arrest in MTLa cells of the mating type locus of Candida albicans.
    SP2
  • HY-119528
    Mansonone F
    		Inhibitor
    Mansonone F is a potent anti-MRSA sesquiterpenoid quinone that can be found in Thespesia populnea.
    Mansonone F
  • HY-N12553
    4-Ethyloctane
    		Inhibitor
    4-Ethyloctane is an active ingredient that can be extracted from peony. 4-Ethyloctane has strong antibacterial activity against Staphylococcus aureus (MIC = 0.04 mg/mL). 4-Ethyloctane can be used for research on bacterial infections.
    4-Ethyloctane
  • HY-149294
    DNA Gyrase-IN-8
    		Inhibitor
    DNA Gyrase-IN-8 is a potent DNA gyrase inhibitor with an IC50 value of 8.45 µM. DNA Gyrase-IN-8 shows antimicrobial activity.
    DNA Gyrase-IN-8
  • HY-P10411
    BING
    		Inhibitor
    BING is an antimicrobial peptide that can be isolated from Japanese medaka fish. BING shows a broad-spectrum toxicity against pathogenic bacteria including drug-resistant strains. BING induces a deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, and reduces the RNA level of cpxR, which plays a crucial role in the development of antimicrobial resistance.
    BING
  • HY-P11182
    ChMAP-28
    		Inhibitor
    ChMAP-28 is an antimicrobial peptide. ChMAP-28 can be derived from goat Capra hircus. ChMAP-28 can initiate necrotic death. ChMAP-28 is effective in killing many bacteria, including strains resistant to Polymyxin and Meropenem (HY-13678). ChMAP-28 shows antitumor activity against acute promyelocytic leukemia, epidermoid carcinoma, melanoma, breast adenocarcinoma.
    ChMAP-28
  • HY-N8762
    3,9-Dihydroxypterocarpan
    		Inhibitor
    3,9-Dihydroxypterocarpan (Demethylmedicarpin) is a Steroids product that can be isolated from the herbs of Nerium indicum Mill..
    3,9-Dihydroxypterocarpan
  • HY-114938
    Fumaramidmycin
    		Inhibitor
    Fumaramidmycin is an antibiotic found in Streptomyces kurssanovii NR-7GG1. Fumaramidmycin shows an antimicrobial activity against both Gram-positive and Gram-negative bacteria.
    Fumaramidmycin
  • HY-N9735
    8-Hydroxy-9,10-diisobutyryloxythymol
    		Inhibitor
    8-Hydroxy-9,10-diisobutyryloxythymol is a natural monoterpenoid with antibacterial properties. 8-Hydroxy-9,10-diisobutyryloxythymol against S. aureus, S. flexneri, and S. paratyphi-B with MIC values of 6.25 μg/mL.
    8-Hydroxy-9,10-diisobutyryloxythymol
  • HY-146199
    Antibacterial agent 108
    		Inhibitor
    Antibacterial agent 108 (Compound 1h) is a potent antibacterial agent with a MIC of both 3 μM against MRSA and antibiotic resistance strains.
    Antibacterial agent 108
  • HY-N7071AR
    Maduramicin ammonium (Standard)
    		Inhibitor
    Maduramicin (ammonium) (Standard) is the analytical standard of Maduramicin (ammonium). This product is intended for research and analytical applications. Maduramicin ammonium (Maduramycin ammonium) is isolated from the actinomycete Actinomadura rubra. Maduramicin ammonium (Maduramycin ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection. Maduramicin ammonium (Maduramycin ammonium) induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways.
    Maduramicin ammonium (Standard)
  • HY-146700
    MtTMPK-IN-6
    		Inhibitor
    MtTMPK-IN-6 (compound 1) is a potent M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC50 value of 29 μM. MtTMPK-IN-6 can be used for researching tuberculosis.
    MtTMPK-IN-6
Cat. No. Product Name / Synonyms Application Reactivity