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Art. -Nr.: HY-N18009

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1-Hydroxy-3,5-dimethoxyxanthone

1-Hydroxy-3,5-dimethoxyxanthone is a xanthone and Antibacterial agent. 1-Hydroxy-3,5-dimethoxyxanthone can be isolated from Lomatogonium rotatum. 1-Hydroxy-3,5-dimethoxyxanthone inhibits the growth of Pseudomonas aeruginosa ATCC27853 and Escherichia coli ATCC25923 with an MIC of 640 μg/mL. 1-Hydroxy-3,5-dimethoxyxanthone exhibits anticancer activity against cervical cancer, breast cancer, melanoma, liver cancer, and gastric cancer.

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CAS. Nr.: 6563-48-0
Formel: C₁₅H₁₂O₅
Molecular Weight:272.25

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

1-Hydroxy-3,5-dimethoxyxanthone Chemical Structure

CAS. Nr.: 6563-48-0

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Biologische Aktivität

Beschreibung

In Vitro

1-Hydroxy-3,5-dimethoxyxanthone (range of concentrations; 48 h) inhibits the growth of HeLa, MCF-7, A375-S2, HepG2, and SGC-7901 cells in vitro, with the strongest activity against SGC-7901 cells (IC₅₀ = 48.74±3.22 μg/mL) after 48 h incubation^[1].
1-Hydroxy-3,5-dimethoxyxanthone (1.25-640 μg/mL; 24 h) inhibits the growth of Pseudomonas aeruginosa ATCC27853 and Escherichia coli ATCC25923 in vitro with an MIC of 640 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 6563-48-0
Molecular Weight 272.25
Formel C₁₅H₁₂O₅
SMILES

O=C1C2=C(OC3=C1C(O)=CC(OC)=C3)C(OC)=CC=C2
Structure Classification
- Phenols
- Xanthones
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Wang M, et al. Structural elucidation and α‑glucosidase inhibitory activity of a new xanthone glycoside from Lomatogonium rotatum (L.) Fries es Nym. Nat Prod Res. 2022 Sep;36(17):4317-4321. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

1-Hydroxy-3,5-dimethoxyxanthone

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1-Hydroxy-3,5-dimethoxyxanthone

Biologische Aktivität

Beschreibung

In Vitro

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

1-Hydroxy-3,5-dimethoxyxanthone Related Classifications

HY-N18009 Related Classifications

Bioz

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