1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W700069
    Gatifloxacin-d4
    Inhibitor
    Gatifloxacin-d4 (AM-1155-d4) is the deuterium labeled Gatifloxacin (HY-10581). Gatifloxacin (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin inhibits bacterial type II topoisomerases (IC50 = 13.8 μg/mL for S. aureus topoisomerase IV) and E.coli DNA gyrase (IC50 = 0.109 μg/mL). Gatifloxacin can be used for the study of bacterial conjunctivitis in vivo.
    Gatifloxacin-d<sub>4</sub>
  • HY-153696
    MRL-436
    Inhibitor
    MRL-436 is a RNA polymerase inhibitor with antibacterial activity. MRL-436 exerts its antibacterial activity dependent on residue 622 of the RNA polymerase β' subunit and the RNAP ω subunit. MRL-436 inhibits Rifampicin (HY-B0272)-resistant RNA polymerase derivatives and exhibits antibacterial activity against Rifampicin-resistant strains.
    MRL-436
  • HY-N14182
    Asparenomycin A
    Inhibitor
    Asparenomycin A is a carbapenem antibiotic with strong β-lactamase inhibition activities.
    Asparenomycin A
  • HY-179632
    Antibacterial agent 311
    Inhibitor
    Antibacterial agent 311 (Compound 4f) is an antibacterial agent. Antibacterial agent 311 exhibits antibacterial activities against P. aeruginosa, S. aureus, E. coli, K. pneumonia, E. CTXM1, E. NDM1 with MICs of 0.8, 1, 1, 1, 0.7, 0.7 mg/mL.
    Antibacterial agent 311
  • HY-N14815
    Nanaomycin D
    Inhibitor
    Nanaomycin D is an antibiotic with antibacterial activity.
    Nanaomycin D
  • HY-N13993
    Aranorosinol A
    Inhibitor
    Aranorosinol A is a secondary metabolite with weak antibacterial and antifungal properties.
    Aranorosinol A
  • HY-N15454
    Altenuisol
    Inhibitor
    Altenuisol is a compound that can be found in the pathogenic fungus of the genus Alternaria in Xanthium italicum. It has herbicidal activity. At a low concentration of Altenuisol (10 μg/mL), it promotes the root growth of Pennisetum alopecuroides and Medicago sativa by 75.2% and 51.0% respectively. At a high concentration of Altenuisol (1000 μg/mL), the inhibition rates of root growth of Pennisetum alopecuroides and Medicago sativa are 52.0% and 42.0% respectively. In addition, Altenuisol is cytotoxic to HeLa cells and also exhibits antibacterial and antioxidant activities. Altenuisol is expected to be used in research in fields such as agricultural weeding, anti - tumor, and anti - infection .
    Altenuisol
  • HY-W753557
    Avocadene
    Inhibitor
    Avocadene is a natural product isolated from Persea americana leaves, with anticancer, insecticidal, anti-Helicobacter pylori, and anti-inflammatory activity. Avocadene exerts antibacterial and anti‑inflammatory effects by suppressing Helicobacter pylori growth and inhibiting protein denaturation. Avocadene displays obvious cytotoxic activity against human prostate cancer PC‑3 cells with an IC50 of 0.5 μg/mL. Avocadene can be used for research of Helicobacter pylori‑associated gastrointestinal inflammation, gastroduodenal injury and prostate tumors.
    Avocadene
  • HY-N14490
    Coumamidine γ1
    Inhibitor
    Coumamidine γ1 is a kind of alkaline sugar Cinodine antibiotic, which has broad spectrum antibacterial activity and also has effect on pseudomonas aeruginosa.
    Coumamidine γ1
  • HY-172250
    8-Hydroxyerythromycin A
    Inhibitor
    8-Hydroxyerythromycin is a semi-synthetic antibiotic with an antibacterial activity.
    8-Hydroxyerythromycin A
  • HY-N14117
    Curvulic acid
    Inhibitor
    Curvulic acid has weak activity against Gram-positive and negative bacteria.
    Curvulic acid
  • HY-151165R
    LasR-IN-3 (Standard)
    Inhibitor
    Quinizarin (Standard) is the analytical standard of Quinizarin. This product is intended for research and analytical applications. Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth.
    LasR-IN-3 (Standard)
  • HY-W013766
    Pipemidic acid trihydrate
    Inhibitor 98.0%
    Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections.
    Pipemidic acid trihydrate
  • HY-13725AR
    Pirarubicin Hydrochloride (Standard)
    Inhibitor
    Pirarubicin (Hydrochloride) (Standard) is the analytical standard of Pirarubicin (Hydrochloride). This product is intended for research and analytical applications. Pirarubicin Hydrochloride is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors.
    Pirarubicin Hydrochloride (Standard)
  • HY-P0274
    PGLa
    Inhibitor
    PGLa, a 21-residue peptide, is an antimicrobial peptide. PGLa is a member of the magainin family of antibiotic peptides found in frog skin and its secretions.
    PGLa
  • HY-U00389
    WQ3810
    Inhibitor
    WQ3810 is an orally active fluoroquinolone, with potent antibacterial activities.
    WQ3810
  • HY-U00194
    Vebufloxacin
    Inhibitor
    Vebufloxacin (Flumenique; OPC7241; DM8966) exhibits potent antibacterial activity against gram-positive and -negative bacteria.
    Vebufloxacin
  • HY-U00214
    Ibafloxacine
    Inhibitor
    Ibafloxacine (R835) is a fluoroquinolone antibiotic agent that is developed exclusively for veterinary use.
    Ibafloxacine
  • HY-U00255
    BO3482
    Inhibitor
    BO3482 has Antimicrobial activity and can inhibit the growth of methicillin-resistant Staphylococci (MRS) with an MIC90 of 6.25 mg/mL.
    BO3482
  • HY-U00380
    Tigemonam
    Inhibitor
    Tigemonam is an orally active monobactam antibiotic with a Ki of 0.86 μM against Enterobacter cloacae P99 β-lactamase and 50.8 μM against Escherichia coli TEM-1 β-lactamase. Tigemonam binds to penicillin-binding proteins 1a, 3, and 4, inhibits bacterial cell wall synthesis, and exhibits bactericidal activity against aerobic gram-negative bacteria including Enterobacteriaceae, Haemophilus influenzae, and Neisseria gonorrhoeae. Tigemonam resists hydrolysis by multiple β-lactamase enzymes, reduces bacterial load in systemic, pyelonephritic, lung, and thigh muscle infections in rodents, and shows minimal difference between minimum inhibitory and bactericidal concentrations. Tigemonam can be used for the research of gram-negative bacterial infections, acute pyelonephritis, lung infection, and thigh muscle infection.
    Tigemonam
Cat. No. Product Name / Synonyms Application Reactivity