2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

Related Products

PDF 14.26 MB

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-149064
    Antituberculosis agent-9
    		Inhibitor
    Antituberculosis agent-9 (Compound 5a) is an orally active antitubercular agent with an MIC of 0.5 μg/mL against H37Ra.
    Antituberculosis agent-9
  • HY-133056
    Pseudomonic acid C
    		Inhibitor 98.0%
    Pseudomonic acid C, an antibiotic, possesses antibacterial activity.
    Pseudomonic acid C
  • HY-161788
    DNA Gyrase-IN-11
    		Inhibitor
    DNA Gyrase-IN-11 (Compound 23Be) is an inhibitor for protein synthesis (IC50 is 0.74 μM) and DNA replication. DNA Gyrase-IN-11 inhibits DNA gyrase, that inhibits E. coli DNA supercoiling with IC50 of 11.9 μM. DNA Gyrase-IN-11 exhibits antibacterial efficacy, that inhibits Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and Staphylococcus aureus, with MICs of 0.008-0.25 μg/mL.
    DNA Gyrase-IN-11
  • HY-P11114
    Periplanetasin-4
    		Inhibitor
    Periplanetasin-4 is an antimicrobial peptide that can be derived from the American cockroach (Periplaneta americana). Periplanetasin-4 reduces cell rounding and apoptosis. Periplanetasin-4 blocks Clostridium difficile toxin A-induced ROS production and the activation of downstream p38 MAPK and p21. Periplanetasin-4 significantly increases mitochondrial calcium level, reduces DPH fluorescence intensity and vacuolar dysfunction in Candida albicans ATCC 90028 cells. Periplanetasin-4 significantly ameliorates toxin A-induced mucosal damage in the mouse gut. Periplanetasin-4 can be used for the study of colitis.
    Periplanetasin-4
  • HY-168204
    3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic acid
    		Inhibitor
    3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid (compound J1) is a potent antimicrobial agent. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid shows anti-gram-positive bacteria and fungi activity. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid can be used as antibiotic adjuvants. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic disrupts the bacterial cell membrane, inserts into the DNA, and binds to DNA gyrase. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic reduces microbial count in a mouse MRSA skin infection model and accelerates wound healing.
    3-Acetyl-28-N-(3-guanidinobutoxy)-oleanolic acid
  • HY-160679
    BaENR-IN-1
    		Inhibitor
    BaENR-IN-1 (Compound 5) is an inhibitor of Enoyl-Acyl Carrier Protein Reductase (ENR) (IC50= 7.7 μM). BaENR-IN-1 blocks the synthesis of fatty acids essential for bacterial growth by inhibiting the bacterial enzyme ENR. BaENR-IN-1 shows activity against bacteria.
    BaENR-IN-1
  • HY-N2980
    Ocotillone
    		Inhibitor
    Ocotillone ((24S)-20,24-Epoxy-25-hydroxydammaran-3-one) is a triterpenoids that can be isolated from the fruits of Dysoxylum richii. Ocotillone has antibacterial activities against P. aeruginosa and S. typhimurium without hemolytic activity.
    Ocotillone
  • HY-176997
    PDHc-E2-IN-1
    		Inhibitor
    PDHc-E2-IN-1 (Compound 9) is a Pyruvate Dehydrogenase Complex E2 (PDHc-E2) inhbibitor. with an IC50 of 2.52 μM. PDHc-E2-IN-1 shows strong antibacterial activity and can be used in the research of bacterial spot disease and bacterial leaf blight in rice.
    PDHc-E2-IN-1
  • HY-170489
    Antifungal agent 123
    		Inhibitor
    Antifungal agent 123 (Compound 4b) exhibits good affinity to the oxidoreductase of Staphylococcus aureus or the membrane protein of Candida albicans, exhibits antibacterial and antifungal activities. Antifungal agent 123 scavenges free radical, exhibits antioxidant efficacy. Antifungal agent 123 inhibits the TLR signaling pathway, and exhibits anti-inflammatory efficacy.
    Antifungal agent 123
  • HY-B0957S
    Erythromycin ethylsuccinate-13C,d3
    		Inhibitor
    Erythromycin ethylsuccinate-13C,d3 is the 13C- and deuterium labeled Erythromycin Ethylsuccinate. Erythromycin Ethylsuccinate is an antibiotic useful for the treatment of a number of bacterial infections, has an antimicrobial spectrum similar to or slightly wider than that of penicillin. Erythromycin Ethylsuccinate has antiviral activity against HIV-1.
    Erythromycin ethylsuccinate-<sup>13</sup>C,d<sub>3</sub>
  • HY-P4301
    Di-aspartic acid
    Di-aspartic acid (Aspartylaspartate) can be utilized as growth substrate for P. gingivalis, P. intermedia, P. nigrescens and F. nucleatum.
    Di-aspartic acid
  • HY-15739R
    Ansamitocin P-3 (Standard)
    		Inhibitor
    Ansamitocin P-3 (Standard) is the analytical standard of Ansamitocin P-3. This product is intended for research and analytical applications. Ansamitocin P-3 (Antibiotic C 15003P3) is a microtubule inhibitor. Ansamitocin P-3 is a macrocyclic antitumor antibiotic.
    Ansamitocin P-3 (Standard)
  • HY-137527
    Ac-Lys(Ac)-D-Ala-D-Ala-OH
    		Activator
    Ac-Lys (Ac)-D-Ala-D-Ala-OH is a synthetic dipeptide analog that mimics the terminal structure of bacterial peptidoglycan chains. Ac-Lys (Ac)-D-Ala-D-Ala-OH serves as a molecular decoy to investigate the mechanism of action of Vancomycin-class antibiotics, and also acts as an affinity chromatography ligand for purifying proteins that bind to Vancomycin. Ac-Lys (Ac)-D-Ala-D-Ala-OH reduces the activity of Vancomycin against susceptible enterococci. Ac-Lys (Ac)-D-Ala-D-Ala-OH is applicable to the research of Vancomycin-resistant enterococcal infections.
    Ac-Lys(Ac)-D-Ala-D-Ala-OH
  • HY-144261
    Metallo-β-lactamase-IN-3
    		Inhibitor
    Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-3 shows high activity against VIM-1 and NDM-1, with IC50 of 0.6 and 1.0 μM, respectively. Metallo-β-lactamase-IN-3 does not show inhibition of IMP-7.
    Metallo-β-lactamase-IN-3
  • HY-139750
    Antibacterial agent 34
    		Inhibitor
    Antibacterial agent 35, an antibacterial agent, significantly lowers MIC value of antibacterial agent Ceftazidime.
    Antibacterial agent 34
  • HY-N3528
    Camaric acid
    		Inhibitor
    Camaric acid can be isolated from the root of Lantana montevidensis and has antibacterial activity.
    Camaric acid
  • HY-157043
    Antibacterial agent 161 trifluoromethanesulfonate
    		Inhibitor
    Antibacterial agent 161 trifluoromethanesulfonate (Compound 6) has antibacterial activity. Antibacterial agent 161 trifluoromethanesulfonate has high antiproliferative effects against colon cancer and non-small cell lung cancer.
    Antibacterial agent 161 trifluoromethanesulfonate
  • HY-N10280
    Asperglaucin A
    		Inhibitor
    Asperglaucin A represents an unusual phthalide-like derivative. Asperglaucin A exhibits potent antibacterial activities against two plant pathogens Pseudomonas syringae pv actinidae (Psa) and Bacillus cereus, with an MIC value of 6.25 μM.
    Asperglaucin A
  • HY-P2458
    CAP18 (rabbit)
    		Inhibitor
    CAP18 (rabbit) is a 37 amino acids antimicrobial peptide originally isolated from rabbit granulocytes. CAP18 (rabbit) has broad antimicrobial activity against both Gram-positive (IC50, 130-200 nM) and Gram-negative (IC50, 20-100 nM) bacteria. CAP18 (rabbit) has the potential for bacterial sepsis research.
    CAP18 (rabbit)
  • HY-N4104R
    Agaric acid (Standard)
    		Inhibitor
    Agaric acid (Standard) (Agaricinic Acid (Standard)) is the analytical standard of Agaric acid (HY-N4104). This product is intended for research and analytical applications. Agaric acid (Agaricinic Acid) is an orally active inhibitor of adenine nucleotide translocase found in specific fungi. Agaric acid can inhibit the biofilm formation of various bacteria such as Salmonella. Agaric acid can also induce mitochondrial permeability transition, prompting mitochondria to release Ca2+, disrupting the transmembrane potential, and causing mitochondrial swelling. In addition, Agaric acid can also inhibit citrate transport in liver mitochondria and participate in the inhibition of fatty acid synthesis, affecting multiple metabolic processes.
    Agaric acid (Standard)
Cat. No. Product Name / Synonyms Application Reactivity