DNA Gyrase-IN-11
DNA Gyrase-IN-11 (Compound 23Be) is an inhibitor for protein synthesis (IC50 is 0.74 μM) and DNA replication. DNA Gyrase-IN-11 inhibits DNA gyrase, that inhibits E. coli DNA supercoiling with IC50 of 11.9 μM. DNA Gyrase-IN-11 exhibits antibacterial efficacy, that inhibits Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and Staphylococcus aureus, with MICs of 0.008-0.25 μg/mL.
For research use only. We do not sell to patients.
- CAS No.: 2497486-58-3
- Formula: C61H84FN7O16
- Molecular Weight:1190.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Chemical Information
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CAS No. 2497486-58-3
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Molecular Weight 1190.36
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Formula C61H84FN7O16
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SMILES
O=C(NC)C1=CC(C#CCO/N=C([C@H](C)C[C@](OC)(C)[C@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@@H](C)[C@H](OC(CCNCCCCNC3=CC4=C(C(C(C(O)=O)=CN4C5CC5)=O)C=C3F)=O)[C@@H](C)C6=O)/[C@@H]([C@@H]7[C@@](OC(O7)=O)(C)[C@@H](CC)O6)C)=CN=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)