1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N19923
    Tercatain
    Inhibitor
    Tercatain is a COVID-19 main protease inhibitor with antibacterial activity. Tercatain exhibits antibacterial activity against Ralstonia solanacearum. Tercatain can be used for the research of COVID-19, and bacterial infections.
    Tercatain
  • HY-155648
    Tuberculosis inhibitor 6
    Inhibitor
    Tuberculosis inhibitor 6 (compound 2c) is a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative that shows highly active against Mycobacterium tuberculosis (MIC90 of ≤1.66 μM) and Mycobacterium marinum (MIC90 of 2.65 μM).
    Tuberculosis inhibitor 6
  • HY-30219R
    D-(+)-Phenyllactic acid (Standard)
    Inhibitor
    D-​(+)​-​Phenyllactic acid (Standard) is the analytical standard of D-​(+)​-​Phenyllactic acid. This product is intended for research and analytical applications. D-​(+)​-​Phenyllactic acid is an anti-bacterial agent, excreted by Geotrichum candidum, inhibits a range of Gram-positive from humans and foodstuffs and Gram-negative bacteria found in humans[1].
    D-(+)-Phenyllactic acid (Standard)
  • HY-146300
    Mt KARI-IN-4
    Inhibitor
    Mt KARI-IN-4 (compound 5c) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) inhibitor with a Ki value of 5.48 μM. Mt KARI-IN-4 has inhibitory activity against Mtb H37Rv (MIC = 0.78 μM) and low cytotoxicity (HEK IC50 > 72 μg/mL).
    Mt KARI-IN-4
  • HY-137371R
    Lactonic sophorolipid (Standard)
    Inhibitor
    Lovastatin hydroxy acid (sodium) (Standard) is the analytical standard of Lovastatin hydroxy acid (sodium). This product is intended for research and analytical applications. Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a Ki of 0.6 nM.
    Lactonic sophorolipid (Standard)
  • HY-139771
    Antibacterial agent 54
    Inhibitor
    Antibacterial agent 54 (example 20) is a antibacterial agent (extracted from patent WO2013030735A1).
    Antibacterial agent 54
  • HY-146463
    NusB-IN-1
    Inhibitor
    NusB-IN-1 (Compound 22r) is a potent, orally active bacterial rRNA synthesis inhibitor. NusB-IN-1 shows antimicrobial activity against MRSA and VRSA. NusB-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    NusB-IN-1
  • HY-126461
    Salazinic acid
    Inhibitor
    Salazinic acid has antibacterial activity against bacteria and fungi. Salazinic acid does not show antibacterial activity against Listeria monocytogenes, Pseudomonas aeruginosa, Yersinia enterocolitica, and Enterococcus faecalis, but it does have antibacterial activity against Pseudomonas aeruginosa and Salmonella typhimurium.
    Salazinic acid
  • HY-14990A
    Sudoterb hydrochloride
    Inhibitor
    Sudoterb (LL 3858) hydrochloride is an orally active anti-Tuberculosis agent.
    Sudoterb hydrochloride
  • HY-163291
    AM4085
    Antagonist
    AM4085 is an orally active Antagonist for FmlH with an IC50 of 0.19 μM. AM4085 reveals metabolic stability in mouse liver microsomes and blood plasma.
    AM4085
  • HY-P5642
    Retrocyclin-101
    Inhibitor
    Retrocyclin-101 (RC-101) is a synthetic cyclic θ-defensin, a broad-spectrum antimicrobial peptide with anti-pathogen (covering viruses, bacteria and fungi) activity and anti-inflammatory activity. Retrocyclin-101 exhibits significant inhibitory activity against HIV, SARS-CoV-2, flaviviruses, influenza viruses, HSV-1/2, Staphylococcus aureus and others. Retrocyclin-101 inhibits TLR4 and TLR2-mediated signal transduction and reduces pro-inflammatory cytokine expression.
    Retrocyclin-101
  • HY-N0312
    Rhein-8-glucoside calcium
    Inhibitor
    Rhein-8-glucoside calcium, an anthraquinone compound, is isolated from the EtOH extract of the roots of Saussurea lappa. Rhein-8-glucoside calcium is an hPTP1B inhibitor, with an IC50 of 11.5 μM. Rhein-8-glucoside calcium has antibacterial effects.
    Rhein-8-glucoside calcium
  • HY-16566AR
    Kanamycin sulfate (Standard)
    Inhibitor
    Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia.
    Kanamycin sulfate (Standard)
  • HY-152668
    Urease-IN-4
    Inhibitor
    Urease-IN-4 is an effective inhibitor of urease with an IC50 value of 1.64 µM. Urease-IN-4 has low cytotoxicity and shows inhibitory activity on P. vulgaris with an IC50 value of 15.27 µg/mL.
    Urease-IN-4
  • HY-E70140
    α-1,4-N-Acetylglucosaminyltransferase 4
    Inhibitor
    α-1,4-N-Acetylglucosaminyltransferase 4 (EC 2.4.1, A4GNT) catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans and suppresses H. pylori growth.
    α-1,4-N-Acetylglucosaminyltransferase 4
  • HY-N13196
    Arcopilin A
    Inhibitor
    Arcopilin A (compound Arcopilin A(1))is an antibacterial agent. Arcopilin A has weak inhibitory effects on fungal pathogens and Gram-positive bacteria, with IC50 values of 8.9 μg/mL and 14 μg/mL for cells KB-3-1 and L929, but it can effectively destroy preformed biofilms of Staphylococcus aureus. Arcopilin A can enhance the activities of gentamicin (GM; HY-K1050) and vancomycin (Vac; HY-B0671) by 115 and 31 times, respectively.
    Arcopilin A
  • HY-19659A
    Fandofloxacin hydrochloride
    Inhibitor
    Fandofloxacin (DW-116) hydrochloride is an orally active quinolone antibiotic. Fandofloxacin hydrochloride is embryotoxic and teratogenic. Fandofloxacin hydrochloride can be used for the research of bacterial infection.
    Fandofloxacin hydrochloride
  • HY-P11251
    RI-18
    Inhibitor
    RI-18 is an antimicrobial peptide. RI-18 exhibits high affinity for bacterial plasma membranes, inducing rapid membrane permeabilization and rupture. RI-18 exhibits potent antimicrobial activity against bacteria in planktonic and biofilmforms.
    RI-18
  • HY-N11733
    D-Glucoheptose
    D-Glucoheptose is a heptose monosaccharide that serves as a starting material for sedoheptulose. D-Glucoheptose has a strong association with the genus Symbiobacterium. The content of D-Glucoheptose in urine of the control group without liver injury is higher than that in the anti-tuberculosis drug-induced liver injury group. D-Glucoheptose can be used in studies related to anti-tuberculosis drug-induced liver injury.
    D-Glucoheptose
  • HY-185443
    UCP1172
    Inhibitor
    UCP1172 is an antibacterial (Antibacterial) agent and Dihydrofolate reductase inhibitor, with an IC50 of 0.0089 μM against Staphylococcus aureus DfrB, 0.22 μM against DfrG, 0.41 μM against DfrA, and 0.030 μM against DfrK. UCP1172 potently inhibits the growth of MRSA/MSSA isolates carrying dfrG and dfrK (MIC values of 0.3125-0.625 μg/mL), shows weak activity against MRSA carrying dfrA (MIC of 5 μg/mL), and exerts extremely potent inhibitory effects on wild-type S. aureus ATCC 43300 (MIC of 0.0098 μg/mL). UCP1172 can be used in studies related to tuberculosis and Staphylococcus aureus infections.
    UCP1172
Cat. No. Product Name / Synonyms Application Reactivity