Tercatain
Tercatain is a COVID-19 main protease inhibitor with antibacterial activity. Tercatain exhibits antibacterial activity against Ralstonia solanacearum. Tercatain can be used for the research of COVID-19, and bacterial infections.
For research use only. We do not sell to patients.
- CAS No.: 103744-87-2
- Formula: C34H26O22
- Molecular Weight:786.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Tercatain (7.8-250 μg/mL; 18-36 h) inhibits the growth of Ralstonia solanacearum with an MIC of 52.1 μg/mL[2].
Tercatain potently binds to the catalytic dyad residues (Cys145 and His41) of SARS-CoV-2 3CLpro, qualifying as a potential natural inhibitor of the viral protease[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 103744-87-2
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Molecular Weight 786.56
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Formula C34H26O22
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SMILES
O[C@H]1[C@H](OC(C2=CC(O)=C(O)C(O)=C2)=O)O[C@H](COC(C3=CC(O)=C(O)C(O)=C3C4=C(O)C(O)=C(O)C=C45)=O)[C@@H](OC(C6=CC(O)=C(O)C(O)=C6)=O)[C@@H]1OC5=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[2]. Vu TT, et al. Antibacterial activity of tannins isolated from Sapium baccatum extract and use for control of tomato bacterial wilt. PLoS One. 2017;12(7):e0181499. Published 2017 Jul 25. [Content Brief]
[3]. Khalifa I, et al. Tannins inhibit SARS-CoV-2 through binding with catalytic dyad residues of 3CLpro: An in silico approach with 19 structural different hydrolysable tannins. J Food Biochem. 2020 Oct;44(10):e13432. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Tercatain
- 103744-87-2
- SARS-CoV
- Bacterial
- Virus Protease
- Xanthomonas arboricola pv. pruni
- Acidovorax avenae subsp. cattleyae
- Cys145
- Pseudomonas syringae pv. actinidiae
- His41
- COVID-19 main protease
- Burkholderia glumae
- Ralstonia solanacearum
- SARS-CoV-2 3CLpro
- SARS-CoV-2 3-chymotrypsin-like cysteine protease
- Inhibitor
- inhibitor
- inhibit