2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0143R
    Phlorizin (Standard)
    		Inhibitor
    Phlorizin (Floridzin) (Standard) is the analytical standard of Phlorizin. This product is intended for research and analytical applications. Phlorizin is an orally active non-selective sodium-glucose cotransporter (SGLT) inhibitor, with an IC50 of 0.04 μM and a Ki of 39 nM against hSGLT2, and an IC50 of 0.17 μM and a Ki of 0.31 μM against hSGLT1. Phlorizin promotes GLUT4 translocation, inhibits gluconeogenesis and promotes glycogen synthesis by activating the PI3K/Akt/mTOR pathway. Phlorizin reduces DNA damage and apoptosis (apoptosis) by inhibiting the NF-κB inflammatory pathway. Phlorizin induces apoptosis via activating the Caspase pathway by antagonizing the JAK/STAT3 and PCK pathways. Phlorizin also exhibits antibacterial, anti-inflammatory and neuroprotective activities.
    Phlorizin (Standard)
  • HY-180451
    Antibacterial agent 310
    		Inhibitor
    Antibacterial agent 310 (compound 2) is a bis-benzimidazole-derived chelating ligand exhibiting antibacterial activity. Antibacterial agent 310 shows inhibition activity against intracellular viruses. Antibacterial agent can be used for antibacterial research.
    Antibacterial agent 310
  • HY-101136
    Dealanylascamycin
    		Inhibitor
    Dealanylascamycin (AT-265) (Compound 2) is a nucleoside antibiotic. AT 265 is a carbonic anhydrase (CA) inhibitor, with Ki values of 167, 65.2, 234, and 143 nM for hCA I, hCA II, hCA IV, and hCA IX respectively. Dealanylascamycin is the active form of Ascamycin (HY-121071). Dealanylascamycin exhibits broad-spectrum antibacterial activity and is effective against pathogenic bacteria such as Xanthomonas citri (MIC = 0.4 μg/mL). Dealanylascamycin has high cytotoxicity.
    Dealanylascamycin
  • HY-N15028
    Depsidomycin
    		Inhibitor
    Depsidomycin is an immunomodulatory antibiotic with immunosuppressive activity that can be isolated from the culture broth of Streptomyces lavendofoliae MI951-62F2. Depsidomycin primarily exhibits antibacterial activity against Gram-positive bacteria.
    Depsidomycin
  • HY-N14871
    Pyrronamycin A
    		Inhibitor
    Pyrronamycin A has antibacterial activity against Gram-positive and negative bacteria such as Staphylococcus aureus, enterococcus, Escherichia coli, Klebsiella pneumoniae, Proteus, Shigella and Salmonella.
    Pyrronamycin A
  • HY-119475
    Satranidazole
    		Inhibitor
    Satranidazole is an orally active insecticide and antimicrobial agent with high electron affinity. Satranidazole forms reduced nitro intermediates, which interact with DNA, causing helix instability, strand breakage and release of thymidine derivatives. Satranidazole exhibits antitrichomonal activity against Trichomonas vaginalis and Trichomonas foetus, and antiamoebic activity in rodent models of hepatic amoebiasis and caecal amoebiasis. Satranidazole inhibits the replication of bacteriophage φX174 DNA. Satranidazole can be used in research related to caecal amoebiasis, trichomoniasis and anaerobic bacterial infections.
    Satranidazole
  • HY-122288
    SC 28538
    		Inhibitor
    SC 28538 is a compound with antimicrobial activity. SC 28538 exerts its antimicrobial effect by reducing its nitro moiety in an anaerobic environment to form cytotoxic free radicals that can damage DNA and other key biomolecules of microorganisms.
    SC 28538
  • HY-118061
    VCC234718
    		Inhibitor
    VCC234718 is a molecule with mycobacterial growth inhibitory activity, specifically targeting Mycobacterium tuberculosis (Mtb). The primary molecular target of VCC234718 is inosine monophosphate dehydrogenase (GuaB2), and it inhibits the growth of Mtb by affecting the function of this enzyme. VCC234718 inhibits GuaB2 with a K value of 100 nM and exhibits non-competitive inhibition with IMP and NAD+. VCC234718 exerts its inhibitory effect by directly interacting with IMP and binding at the NAD+ site.
    VCC234718
  • HY-N14334
    Halomicin B
    		Inhibitor
    Halomicin B is an ansamycin antibiotic. Halomicin B has activity against Gram-positive and Gram-negative bacteria (individual).
    Halomicin B
  • HY-N14111
    Cuevaene A
    		Inhibitor
    Cuevaene A can be isolated from the strain of gdmAI-disrupted Streptomyces sp. LZ35 and. Cuevaene A displays moderate activity against Gram-positive bacteria (e.g., Bacillus subtilis strain ATCC 11060) and modest activity against fungi (e.g., Fusarium verticillioides strain S68 and Rhizoctonia solani strain GXE4).
    Cuevaene A
  • HY-P5725
    Aurein 2.1
    		Inhibitor
    Aurein 2.1 is an antibiotic peptide that can be found in the Australian Bell Frogs Litoria aurea and Litoria raniformis.
    Aurein 2.1
  • HY-168123
    Antitubercular agent-47
    		Inhibitor
    Antitubercular agent-47 (compund 5C) shows potent activity against tuberculosis and was effective against DS/MDR/XDR clinical isolates.
    Antitubercular agent-47
  • HY-N15526
    Austroside A
    		Inhibitor
    Austroside A is found in Evodia austrosinensis. Austroside A shows antibacterial activity against the Staphylococcus aureus antibiotic resistant strain.
    Austroside A
  • HY-N15022
    Azirinomycin
    		Inhibitor
    Azirinomycin has anti-Gram positive and negative bacterial activity.
    Azirinomycin
  • HY-N14067
    Cytosaminomycin A
    		Inhibitor
    Cytosaminomycin A is an antibiotic with anticoccidial and antibacterial activities.
    Cytosaminomycin A
  • HY-122386
    Kirromycin
    		Inhibitor
    Kirromycin (Mocimycin; Delvomycin) is an elongation factor Tu (EF-Tu) inhibitor targeting protein biosynthesis. As an antibiotic, Kirromycin exerts antibacterial activity against Gram-negative bacteria by acting on EF-Tu to interfere with the peptidyl transfer reaction. Kirromycin is applicable to studies on bacterial infections.
    Kirromycin
  • HY-N14237
    Epoxyquinomicin A
    		Inhibitor
    Epoxyquinomicin A is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin A exhibits inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida and Staphylococcus aureus with a MIC of 3-12.5 µg/mL. Epoxyquinomicin A exhibits cytotoxicity in cancer cell L1210, B16 and S180 with IC50 of 2-8 µg/mL. Epoxyquinomicin A exhibits anti-inflammatory effects against collagen-induced arthritis.
    Epoxyquinomicin A
  • HY-163843
    Antibacterial agent 234
    		Inhibitor
    Antibacterial agent 234 (6p) is an antibacterial agent. Antibacterial agent 234 (6p) exhibits good activity against Klebsiella pneumoniae with a MIC value of 6.25 µg/mL.
    Antibacterial agent 234
  • HY-B0656AS3
    Rabeprazole-13C,d3 sodium
    Rabeprazole-13C,d3 (sodium) (LY307640-13C,d3 (sodium)) is 13C labeled Rabeprazole (sodium). Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux.
    Rabeprazole-<sup>13</sup>C,d<sub>3</sub> sodium
  • HY-N14507
    Mycinamicin VII
    		Inhibitor
    Mycinamicin VII is a macrolide antibiotic. Mycinamicin VII shows activity against Gram-positive bacteria.
    Mycinamicin VII
Cat. No. Product Name / Synonyms Application Reactivity