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Cinerubin R
0 ImagesCat. No.: HY-N14106CAS No.: 147657-35-0Cinerubin R has anti-Gram-positive bacteria and inhibition of tumor cell activity, and its inhibition effect on multidrug resistant (MDR) cells is the same as that on protocells. -
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Antimicrobial agent-34
0 ImagesCat. No.: HY-161988CAS No.: 3055131-42-2Antimicrobial agent-34 (compound 4h) is an antibacterial agent (MIC = 1–4 μg/mL), with a clogP value of 9.14. Antimicrobial agent-34 has good plasma stability (HC50 of 131.1 μg/mL) and good membrane selectivity (HC50/MIC is 65.6), with rapid sterilization capability. Antimicrobial agent-34 destroys the integrity of bacterial cell membranes, induces an increase in intracellular reactive oxygen species, and leaks protein and DNA, ultimately leading to bacterial death. Antimicrobial agent-34 demonstrates significant in vivo antibacterial potency in a mouse sepsis model infected with Staphylococcus aureus ATCC43300. -
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Basidalin
0 ImagesCat. No.: HY-N14787CAS No.: 82501-56-2Basidalin has the ability of anti-Gram-positive bacteria, negative bacteria and inhibition of mouse leukemia L-1210 cell. -
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Cefditoren-d3 sodium
0 ImagesCat. No.: HY-W740028Synonyms: ME 1206-d3Cefditoren-d3 (sodium) (ME 1206-d3) is deuterium labeled Cefditoren (sodium). Cefditoren sodium (ME 1206) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren sodium has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren sodium can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections. -
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Antibacterial agent 172
0 ImagesCat. No.: HY-163142CAS No.: 3023114-93-1Antibacterial agent 172 (Compound 6a) is a <,i>Clostridioides difficile (Cd) SpoVD inhibitor (IC50=89 nM) that effectively inhibits sporulation of Clostridioides difficile. Antibacterial agent 172 can be used in the study of bacterial infections. -
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- Meralein sodium
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Mtb-IN-10
0 ImagesCat. No.: HY-170970Mtb-IN-10 (Compound P15) is a Rv1625c/Cya activator that regulates cAMP metabolism to influence the growth of Mycobacterium tuberculosis (Mtb). Mtb-IN-10 exhibits an EC50 of 1.96 µM in an Mtb-infected macrophage model and demonstrates 58.0% oral bioavailability in mice at a 20 mg/kg dose. It may regulate intracellular signaling and disrupt cholesterol metabolism in Mtb, thereby inhibiting bacterial proliferation. Mtb-IN-10 holds potential for tuberculosis (TB) research, particularly for combating multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) Mtb strains. -
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Quabodepistat-d7
0 ImagesCat. No.: HY-134940SSynonyms: OPC-167832-d7Quabodepistat-d7 (OPC-167832-d7) is deuterium labeled Quabodepistat. Quabodepistat (OPC-167832) is a potent and orally active dprE1 inhibitor with?an IC50 of 0.258 μM. Quabodepistat has antituberculosis activity and can be used for the research of tuberculosis?caused by?Mycobacterium tuberculosis. -
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Bromodiphenhydramine hydrochloride (Standard)
0 ImagesCat. No.: HY-B1568ARCAS No.: 1808-12-4Synonyms: Ambodryl hydrochloride (Standard)Bromodiphenhydramine (hydrochloride) (Standard) is the analytical standard of Bromodiphenhydramine (hydrochloride). This product is intended for research and analytical applications. Bromodiphenhydramine hydrochloride is a potent antihistamine with antimicrobial property. Bromodiphenhydramine hydrochloride inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine hydrochloride can be used for cutaneous allergies research. -
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Helvecardin B
0 ImagesCat. No.: HY-N14675CAS No.: 119979-34-9Helvecardin B is a glycopeptidtic antibiotic. Helvecardin B has strong activity of anti-aerobic and anaerobic Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus. -
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Ceforanide (Standard)
0 ImagesCat. No.: HY-B1297RCAS No.: 60925-61-3Ceforanide (Standard) is the analytical standard of Ceforanide. This product is intended for research and analytical applications. Ceforanide is a semisynthetic parental cephalosporin antibiotic, derived from 7-aminocephalosporanic acid. Ceforanide has antibacterial activity and is a potent inhibitor of most species of streptococci, excluding enterococci. -
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Pyrrolomycin C
0 ImagesCat. No.: HY-N14576CAS No.: 81910-06-7Pyrrolomycins C is a member of the pyrrolomycin group of antibiotic found in the Actinosporangium sp. -
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RWJ-60475
0 ImagesCat. No.: HY-135477CAS No.: 204130-08-5RWJ-60475 is a cell-permeable tyrosine phosphatase inhibitor with an IC50 of 3.3 μM. RWJ-60475, by inhibiting the activity of CD45/CD148 phosphatase, interferes with the phagocytic function of macrophages, thereby blocking the invasion of Legionella pneumophila into host cells and the transport of effector proteins. RWJ-60475 significantly reduces the uptake of bacterial particles by macrophages. RWJ-60475 can be used in the research of anti-infection targeting host factors. -
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Napyradiomycin B3
0 ImagesCat. No.: HY-N14805CAS No.: 103106-22-5Napyradiomycin B3 is an antibiotic with anti-Gram-positive bacteria and mycobacterial activity. -
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Ochracenomicin C
0 ImagesCat. No.: HY-N14347CAS No.: 164177-47-3Ochracenomicin C is found in the strain of Amicolatopsis sp. MJ 950-891. Ochracenomicin C has a weak antibacterial effect. -
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Ilicicolin B
0 ImagesCat. No.: HY-114708CAS No.: 22581-07-3Synonyms: LL-Z 1272βIlicicolin B (LL-Z 1272β) inhibits Bacillus carbonifera with the concentration of 6 μg/mL and its toxic concentration to Hela cells is 0.3 μg/mL. -
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LysRs-IN-4
0 ImagesCat. No.: HY-175503CAS No.: 2973324-63-7LysRS-IN-4 (Compound 49) is an orally active Mycobacterium tuberculosis LysRS (lysyl-tRNA synthetase) inhibitor. LysRS-IN-4 is promising for research of tuberculosis. -
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Antibacterial agent 282
0 ImagesCat. No.: HY-174326Antibacterial agent 282 (Compound CP7), a seleno-Ciprofloxacin (HY-B0356) derivative, is an Antibacterial agent. Antibacterial agent 282 has significant antibacterial activity against gram-positive bacterium and gram-negative bacterium with MICs of 0.1-1.56 and 0.1-3.13 μg/mL, respectively (MBCs of 0.2-1.56 and 0.39-12.5 μg/mL). Antibacterial agent 282 potently disrupts and prevents biofilms formation of P. aeruginosa. Antibacterial agent 282 shows significant inhibitory activity towards the DNA gyrase from E. coli. -
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NSC10010 hydrochloride
0 ImagesNSC10010 hydrochloride inhibits gammaherpesvirus associated B-lymphomas growth through activation of NF-kB and c-Myc-mediated signaling pathways. NSC10010 hydrochloride induces necrotic cell death in gammaherpesvirus infected B-cells. NSC10010 hydrochloride is also an inhibitor of Mtb ClpC1 ATPase. -
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Antimycobacterial agent-14
0 ImagesCat. No.: HY-179532Antimycobacterial agent-14 (compound 20s) is an antimycobacterial agent with potent activity against Mycobacterium tuberculosis (M.tb) H37Ra strain with a MIC of 11.37 μM. Antimycobacterial agent-14 can be used for tuberculosis (TB) research. -
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