1. Signalwege
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Art. -Nr. Produktname Wirkung Reinheit Chemical Structure
  • HY-B0935R
    Benzyl benzoate (Standard)
    Inhibitor
    Benzyl benzoate (Standard) is the analytical standard of Benzyl benzoate. This product is intended for research and analytical applications. Benzyl benzoate (Phenylmethyl benzoate) is an orally active anti-scabies agent, acaricide (EC50= 0.06 g/m2) and fungicide. Benzyl benzoate is an angiotensin II (Ang II) inhibitor with antihypertensive effects. Benzyl benzoate can be used in perfumes, pharmaceuticals and the food industry.
    Benzyl benzoate (Standard)
  • HY-171457
    WR-27653
    Inhibitor
    WR-27653 (RC-12) is a derivative of Catechol with good activity against hypnozoites in the gold-standard Plasmodium cynomolgi-rhesus monkey (Macaca mulatta) model. WR-27653 has antimalarial activity.
    WR-27653
  • HY-N15092
    Milbemycin α11
    Inhibitor
    Milbemycin α11 (Meilingmycin A) is an antibiotic and has the effect of killing nematodes and mites.
    Milbemycin α11
  • HY-N0914R
    Ajugol (Standard)
    Inhibitor
    Ajugol (Standard) is the analytical standard of Ajugol (HY-N0914). This product is intended for research and analytical applications. Ajugol is an orally active iridoid glycoside found in the traditional Chinese medicine Leonurus japonicus. Ajugol is an autophagy activator. Ajugol activates TFEB-mediated autophagy and lysosomal biogenesis. Ajugol also has anti-inflammatory effects. Ajugol has great potential in the research of asthma, non-alcoholic fatty liver disease (NAFLD), and osteoarthritis.
    Ajugol (Standard)
  • HY-116021
    Buquinolate
    Inhibitor
    Buquinolate is a quinoline derivative. Buquinolate is effective in preventing coccidiosis of chickens.
    Buquinolate
  • HY-N14745
    Elaiomycin
    Inhibitor
    Elaiomycin has activity against Gram-positive bacteria, some anaerobic bacteria, Eimeria tenella, E.acervulina.
    Elaiomycin
  • HY-B0846R
    Dimethomorph (Standard)
    Dimethomorph (Standard) is the analytical standard of Dimethomorph. This product is intended for research and analytical applications. Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM.
    Dimethomorph (Standard)
  • HY-19502R
    Artemisone (Standard)
    Inhibitor
    Artemisone (Standard) is the analytical standard of Artemisone. This product is intended for research and analytical applications. Artemisone (Artemifone) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains, with a mean IC50 of 0.83 nM. Artemisone is also a potent inhibitor of human CMV.
    Artemisone (Standard)
  • HY-175732
    PI4Kβ-IN-1
    Inhibitor
    PI4Kβ-IN-1 is an orally active and selective PI4Kβ inhibitor, with an IC50 of 0.9 nM. PI4Kβ-IN-1 exhibits inhibitory activity against all stages of the P. falciparum life cycle, including blood, liver, and transmission stages. PI4Kβ-IN-1 demonstrates potent antimalarial efficacy in the mouse model infected with Plasmodium falciparum. PI4Kβ-IN-1 can be used for the study of malaria caused by Plasmodium falciparum.
    PI4Kβ-IN-1
  • HY-124495
    Butocarboxim
    Butocarboxime serves as both an insecticide and acaricide.
    Butocarboxim
  • HY-N5018R
    Nepodin (Standard)
    Inhibitor
    Nepodin (Standard) is the analytical standard of Nepodin. This product is intended for research and analytical applications. Nepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor isolate from Rumex crispus.Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK.Nepodin (Musizin) has antidiabetic and antimalarial activities.
    Nepodin (Standard)
  • HY-N1708
    27-Hydroxymangiferonic acid
    27-Hydroxymangiferonic acid is a Triterpenoids product that can be isolated from the herbs of Mangifera indica.
    27-Hydroxymangiferonic acid
  • HY-120002
    Proclonol
    Inhibitor
    Proclonol (Kilacar) is an insecticide-acaricide. Proclonol is a weak mutagen in the TA97 strain of S. typhimurium.
    Proclonol
  • HY-117397R
    Fenazaquin (Standard)
    Inhibitor
    Fenazaquin (Standard) is the analytical standard of Fenazaquin. This product is intended for research and analytical applications. Fenazaquin (XDE-436; EL-436) is a quinazoline acaricide.
    Fenazaquin (Standard)
  • HY-183009
    Pf20S-IN-1
    Inhibitor
    Pf20S-IN-1 is a selective inhibitor of the 20S proteasome β5 subunit of Plasmodium falciparum. Pf20S-IN-1 exhibits antiparasitic activity against Plasmodium falciparum, with an EC50 of 20.1 nM against the Plasmodium falciparum W2 strain. Pf20S-IN-1 shows weak inhibitory effect on human 20S proteasome, has no obvious toxicity to human foreskin fibroblasts (HFF), and has a selectivity index > 25000. Pf20S-IN-1 can be used in malaria research.
    Pf20S-IN-1
  • HY-107532R
    N-Nonyldeoxynojirimycin (Standard)
    Inhibitor
    N-Nonyldeoxynojirimycin (Standard) is the analytical standard of N-Nonyldeoxynojirimycin (HY-107532). This product is intended for research and analytical applications. N-Nonyldeoxynojirimycin (NN-DNJ) is a deoxynojirimycin derivative with a hydrophobic long chain. N-Nonyldeoxynojirimycin is an orally active inhibitor of acid α-glucosidase (IC50: 0.42 μM) and α-1,6-glucosidase (IC50: 8.4 μM). N-Nonyldeoxynojirimycin has activities of inhibiting glycogen breaKdown, anti-virus and anti-tumor. N-Nonyldeoxynojirimycin also has insecticidal effects, with an LD50 of 5 mM for adults of Bemisia tabaci.
    N-Nonyldeoxynojirimycin (Standard)
  • HY-183238
    Antimalarial agent 61
    Inhibitor
    Antimalarial agent 61 is an antimalarial agent. Antimalarial agent 61 disrupts hemoglobin breakdown in Plasmodium falciparum asexual blood stage trophozoites. Antimalarial agent 61 exerts antiplasmodial activity against Chloroquine (HY-17589A)-sensitive Plasmodium falciparum parasites. Antimalarial agent 61 can be used for the research of malaria.
    Antimalarial agent 61
  • HY-B0806AS
    Proguanil-d4 hydrochloride
    Inhibitor
    Proguanil-d4 (hydrochloride) is the deuterium labeled Proguanil hydrochloride. Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor.
    Proguanil-d<sub>4</sub> hydrochloride
  • HY-N0325R
    DL-Methionine (Standard)
    Inhibitor
    DL-Methionine (Standard) is the analytical standard of DL-Methionine. This product is intended for research and analytical applications. DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants.
    DL-Methionine (Standard)
  • HY-183574
    Antimalarial agent 62
    Inhibitor
    Antimalarial agent 62 is an orally active imidazopyridine-6-carboxamide antimalarial agent with a high resistance barrier. Antimalarial agent 62 kills trophozoite-stage Plasmodium ring forms, effectively clears dihydroartemisinin-induced dormant Plasmodium ring forms, and eliminates parasitemia in mice infected with Plasmodium yoelii. In AReBaR resistance omics screening, Antimalarial agent 62 is not affected by different target- and efflux-mediated resistance mutations and can withstand resistance selection. Antimalarial agent 62 has been applied to studies of malaria-related mechanisms.
    Antimalarial agent 62

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