WR-27653
WR-27653 (RC-12) is a derivative of Catechol with good activity against hypnozoites in the gold-standard Plasmodium cynomolgi-rhesus monkey (Macaca mulatta) model. WR-27653 has antimalarial activity.
For research use only. We do not sell to patients.
- CAS No.: 6042-36-0
- Formula: C20H36BrN3O2
- Molecular Weight:430.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 6042-36-0
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Molecular Weight 430.42
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Formula C20H36BrN3O2
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SMILES
BrC1=C(N(CCN(CC)CC)CCN(CC)CC)C=C(OC)C(OC)=C1
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Synonyms
RC-12
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Dong Y, et al. Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12). ACS Omega. 2022 Mar 30;7(14):12401-12411. [Content Brief]
[2]. Werbel LM, et al. Synthesis and physical properties of the antimalarial agent 4-(2-bromo-4,5-dimethoxyphenyl)-1,1,7,7-tetraethyldiethylenetriamine (RC-12) (WR-27,653). J Pharm Sci. 1967 Oct;56(10):1335-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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