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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-131603B
    Lamivudine triphosphate TEA
    Lamivudine triphosphate (3TCTP) TEA is a phosphorylated Lamivudine (HY-B0250) (a nucleoside analogue). Lamivudine triphosphate TEA inhibits the reverse transcriptase of HIV or HBV viruses to block viral replication by chain termination. Lamivudine triphosphate TEA is also an inhibitor of the RdRp activity of the NS5B subunit of the HCV. Lamivudine triphosphate TEA can be incorporated into the nascent RNA by the SARS-CoV-2 RdRp, thus halting mutations in the nascent SARS-CoV-2 RNA.
    Lamivudine triphosphate TEA
  • HY-186131
    Val-CDCA
    Val-CDCA is a chenodeoxycholate (CDCA) and C-24 L-Valine (HY-N0717) conjugate. Val-CDCA inhibits taurocholate uptake in human NTCP-stably transfected HEK293 cells. Val-CDCA can be used for HBV infection.
    Val-CDCA
  • HY-W777870
    1-Palmitoyl-2-linoleoyl-3-chloropropanediol
    		99.4%
    1-Palmitoyl-2-linoleoyl-3-chloropropanediol is an ester product.
    1-Palmitoyl-2-linoleoyl-3-chloropropanediol
  • HY-W588243
    Δ7-Stigmasterol
    Δ7-Stigmasterol is the major sterols of an amoeba.
    Δ7-Stigmasterol
  • HY-W346976
    8-Iso-15-keto prostaglandin E2
    8-Iso-15-keto prostaglandin E2 is a fatty acyl.
    8-Iso-15-keto prostaglandin E2
  • HY-W015467
    Pyridine-3-sulfonic acid
    		98.0%
    Pyridine-3-sulfonic acid (Pyridine-3-sulphonic acid) is an orally active structural analog of Nicotine acid (HY-B0143). Pyridine-3-sulfonic acid significantly reduces hepatic cholesterol synthesis in rats but lacks cholesterol-lowering activity. Pyridine-3-sulfonic acid does not interfere with the metabolism of Nicotine acid.
    Pyridine-3-sulfonic acid
  • HY-116711
    11-cis-Retinal
    11-cis-Retinal (11-cis Retinaldehyde; 11-cis Vitamin A aldehyde), oxidized form of 11-cis-Retinol (HY-W587807), is a naturally occurring visual component. 11-cis-Retinal binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. 11-cis-Retinal plays a crucial role in vision, growth and development. 11-cis-Retinal can restore visual function in moths with visual impairments. 11-cis-Retinal can restore retinal function in an early-age LCA2 retinal degeneration 12 mouse model.
    11-cis-Retinal
  • HY-W010778
    N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine
    		99.65%
    N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-quinazolin-4-amine is a quinazoline derivative that has also been used in the design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.
    N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine
  • HY-W711045
    Deoxygeraniol
    Deoxygeraniol, a monoterpenoid, has been reported in Camellia sinensis, Magnolia sieboldii, and Zingiber officinale. It is commonly used as an intermediate in the synthesis of fragrances or flavorings.
    Deoxygeraniol
  • HY-W016474A
    1-(4-Fluorophenyl)piperazine hydrochloride
    		99.59%
    1-(4-Fluorophenyl)piperazine (1-(4-Fluorophenyl)piperazinediium) hydrochloride is a substituted phenylpiperazine.
    1-(4-Fluorophenyl)piperazine hydrochloride
  • HY-W074305
    4H-Pyran-4-one
    		99.81%
    4H-pyran-4-one (γ-Pyrone) is a cyclic conjugated pyranone compound.
    4H-Pyran-4-one
  • HY-133630
    1-Bromo-1,1-dichloroacetone
    1-Bromo-1,1-dichloroacetone is one of the clorine doxide dsinfection bproducts (DBPs) in drinking water.
    1-Bromo-1,1-dichloroacetone
  • HY-W131227
    Ethyl 3,5-dihydroxybenzoate
    		99.57%
    Ethyl 3,5-dihydroxybenzoate is an active compound. Ethyl 3,5-dihydroxybenzoate can be used for the research of various biochemical studies.
    Ethyl 3,5-dihydroxybenzoate
  • HY-W007972
    Methyl 3-methoxyacrylate
    		98.96%
    Methyl 3-methoxyacrylate (3-Methoxyacrylic Acid Methyl Ester) is a Lignans product that can be isolated from the herbs of Lysimachia clethroides.
    Methyl 3-methoxyacrylate
  • HY-156777
    Antiproliferative agent-36
    		98.0%
    Antiproliferative agent-36 (compound 8i) is a benzothiazolyl hydrazones derived compound with antiproliferative activity. Antiproliferative agent-36 has a broad-spectrum anticancer activity.
    Antiproliferative agent-36
  • HY-W441002
    DSPE-succinic acid
    		99.72%
    DSPE-succinic acid is a derivative of Succinic acid (HY-N0420) and an intermediate of DSPE-Doxorubicin. DSPE-succinic acid can be used to synthesize DSPE-Doxorubicin via EDC/NHS activation. DSPE-succinic acid is applicable to the research of triple-negative breast cancer.
    DSPE-succinic acid
  • HY-W460119
    Dimethyl pentadecanedioate
    		99.86%
    Dimethyl pentadecanedioate (Pentadecanedioic acid,1,15-dimethyl ester) is an ester product.
    Dimethyl pentadecanedioate
  • HY-W422109
    4-(6-Methyl-1,2,4,5-tetrazin-3-yl)benzoic acid
    4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid is an asymmetric tetrazine derivative and a bioorthogonal reaction partner. 4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid can be conjugated with Bevacizumab (HY-P9906) via EDC/NHS activation while retaining the VEGF-binding affinity of the antibody, thus constructing a targeting agent for pretargeted immuno-PET/NIRF imaging.
    4-(6-Methyl-1,2,4,5-tetrazin-3-yl)benzoic acid
  • HY-N1023
    11-O-Galloylbergenin
    		99.51%
    11-O-Galloylbergenin is a compound isolated from ethanolic extract of Mallotus philippinensis. 11-O-Galloylbergenin has analgesic and anti-inflammatory activities. 11-O-Galloylbergenin is a lead compound for management of pain and inflammation.
    11-O-Galloylbergenin
  • HY-W048341
    3-Ethoxybenzoic acid
    		98.74%
    3-Ethoxybenzoic acid is a derivative of benzoic acid and serves as both a raw material and an intermediate in organic synthesis.
    3-Ethoxybenzoic acid