Antiproliferative agent-36
Based on 1 Customer Validation
Antiproliferative agent-36 (compound 8i) is a benzothiazolyl hydrazones derived compound with antiproliferative activity. Antiproliferative agent-36 has a broad-spectrum anticancer activity.
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- Pureza : 98.0%
- No. CAS: 193828-76-1
- Fòrmula: C13H11N5S
- Peso molecular:269.33
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
Chemical Information
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No. CAS 193828-76-1
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Appearance Solid
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Peso molecular 269.33
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Fòrmula C13H11N5S
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Color Light yellow to yellow
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SMILES
C/C(C1=NC=NC=C1)=N\NC2=NC3=CC=CC=C3S2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (371.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocolo
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7129 mL | 18.5646 mL | 37.1292 mL | 92.8229 mL |
| 5 mM | 0.7426 mL | 3.7129 mL | 7.4258 mL | 18.5646 mL | |
| 10 mM | 0.3713 mL | 1.8565 mL | 3.7129 mL | 9.2823 mL | |
| 15 mM | 0.2475 mL | 1.2376 mL | 2.4753 mL | 6.1882 mL | |
| 20 mM | 0.1856 mL | 0.9282 mL | 1.8565 mL | 4.6411 mL | |
| 25 mM | 0.1485 mL | 0.7426 mL | 1.4852 mL | 3.7129 mL | |
| 30 mM | 0.1238 mL | 0.6188 mL | 1.2376 mL | 3.0941 mL | |
| 40 mM | 0.0928 mL | 0.4641 mL | 0.9282 mL | 2.3206 mL | |
| 50 mM | 0.0743 mL | 0.3713 mL | 0.7426 mL | 1.8565 mL | |
| 60 mM | 0.0619 mL | 0.3094 mL | 0.6188 mL | 1.5470 mL | |
| 80 mM | 0.0464 mL | 0.2321 mL | 0.4641 mL | 1.1603 mL | |
| 100 mM | 0.0371 mL | 0.1856 mL | 0.3713 mL | 0.9282 mL |
Antiproliferative agent-36 Related Classifications
HY-156777 Related Classifications
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