2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3818):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-129290
    Flamprop-methyl
    Flamprop-methyl is an active compound.
    Flamprop-methyl
  • HY-49460
    WAY-639299
    		98.0%
    WAY-639299 is an active molecule for research into amyloid diseases and synucleinopathies.
    WAY-639299
  • HY-N16498
    Kaempferol 3-rungioside
    		Inhibitor
    Kaempferol 3-rungioside is a glycoside derivative of Kaempferol (HY-14590).
    Kaempferol 3-rungioside
  • HY-N17570
    23α-Hydroxy-olean-12-en-3-one
    23α-Hydroxy-olean-12-en-3-one (Compound 15) is a pentacyclic triterpenoid, which is a natural derivative of the oleanane skeleton.
    23α-Hydroxy-olean-12-en-3-one
  • HY-N18121
    Taxinine A
    Taxinine A is a taxoid with a 6/8/6-membered ring system found in Taxus cuspidata. Taxinine A shows little or no effect against Ca2+-induced microtubule depolymerization.
    Taxinine A
  • HY-W674257
    WAY-658674
    		98.0%
    WAY-658674 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-658674
  • HY-181443
    15(S)-15-Methyl Prostaglandin F2α ethyl amide
    15(S)-15-Methyl Prostaglandin F2α ethyl amide (15-Methyl Prostaglandin F2α ethyl amide) is a synthetic Prostaglandin F2α (HY-12956) analogue that stimulates uterine contractions. 15(S)-15-Methyl Prostaglandin F2α ethyl amide can be used for the research of second-trimester pregnancy loss.
    15(S)-15-Methyl Prostaglandin F2α ethyl amide
  • HY-N2792
    9-Deoxygoniopypyrone
    9-Deoxygoniopypyrone is a natural phenolic compound.
    9-Deoxygoniopypyrone
  • HY-174240
    Anticancer agent 274
    Anticancer agent 274 (Compound 1) is a Sorafenib (HY-10201) analog. Anticancer agent 274 can inhibit the growth of tumor cells, with IC50 values of 0.034 μM and 0.042 μM against SaOS-2 and MNNG-HOS cells, respectively. Anticancer agent 274 has relatively low toxicity to normal cells and can be used in the research of tumors such as osteosarcoma.
    Anticancer agent 274
  • HY-N16757
    16-O-Acetylpolyporenic acid C
    16-O-Acetylpolyporenic acid C is a natural triterpene.
    16-O-Acetylpolyporenic acid C
  • HY-N8906
    Stachartin D
    Stachartin D is a natural sesquiterpene.
    Stachartin D
  • HY-182558
    Nandinine
    Nandinine is an orally active derivative of Berberine (HY-N0716). Nandinine enhances AMPK activity, inhibits the activation of IKKβ/NF-κB, and regulates the phosphorylation of IRS-1. Nandinine reverses the abnormal production of adipokines, promotes insulin-mediated glucose uptake, and alleviates insulin resistance. Nandinine improves glucose tolerance and increases the insulin sensitivity index in mice. Nandinine can be used in studies related to insulin resistance.
    Nandinine
  • HY-N17208
    Isosyringinoside
    Isosyringinoside is a natural phenylacetylene.
    Isosyringinoside
  • HY-N17122
    Wedelobatin B
    Wedelobatin B is a natural diterpene.
    Wedelobatin B
  • HY-N16934
    Ampelopsin BF
    Ampelopsin BF is a natural phenolic compound.
    Ampelopsin BF
  • HY-W750691
    Citranaxanthin
    Citranaxanthin is a carotenoid that can be isolated from Sea Hare Dolabella auriculari. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition.
    Citranaxanthin
  • HY-N13752
    Isodihydrocadambine
    Isodihydrocadambine is a natural alkaloid.
    Isodihydrocadambine
  • HY-165624A
    (S)-LY-41
    (S)-LY-41, R-enantiomer of LY-41 (HY-165624), is 2-Sminotetralin (HY-W022362) derivative and 8-OH-DPAT (HY-112061) analogue. (S)-LY-41 is a potent and selective 5-HT1A receptor agonist. (S)-LY-41 can reduce the accumulation of 5-hydroxytryptophan (the precursor for 5-HT synthesis) in the rat brain induced by decarboxylase inhibitors (NSD 1015). (S)-LY-41 can lower the body temperature of rats and inhibit the escape response from the cage. (S)-LY-41 can induce the 5-HT behavioral syndrome. (S)-LY-41can be used for the research of neurological disease, such as depression and anxiety.
    (S)-LY-41
  • HY-N17118
    21,23-Dihydro-21-hydroxy-23-oxonomilinic acid methyl ester
    21,23-Dihydro-21-hydroxy-23-oxonomilinic acid methyl ester is a natural triterpene.
    21,23-Dihydro-21-hydroxy-23-oxonomilinic acid methyl ester
  • HY-116509
    Linoleylanilide
    Linoleylanilide (Linoleic acid anilide) is a Linoleic acid (HY-N0729) derivative. Linoleylanilide slightly inhibits the PMA (HY-18739)-induced expression of CD11b. Linoleylanilide inhibits serum LDH, GOT and GPT activities. Linoleylanilide decreases red cell counts and hemoglobin content.
    Linoleylanilide