Anticancer agent 274
Anticancer agent 274 (Compound 1) is a Sorafenib (HY-10201) analog. Anticancer agent 274 can inhibit the growth of tumor cells, with IC50 values of 0.034 μM and 0.042 μM against SaOS-2 and MNNG-HOS cells, respectively. Anticancer agent 274 has relatively low toxicity to normal cells and can be used in the research of tumors such as osteosarcoma.
For research use only. We do not sell to patients.
- Formula: C21H19N3O3
- Molecular Weight:361.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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Molecular Weight 361.39
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Formula C21H19N3O3
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SMILES
CC(NC1=CC=C(C=C1)OC2=CC=C(C=C2)NC(NC3=CC=CC=C3)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 274 Related Classifications
HY-174240 Related Classifications
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