Taxinine A
Taxinine A is a taxoid with a 6/8/6-membered ring system found in Taxus cuspidata. Taxinine A shows little or no effect against Ca2+-induced microtubule depolymerization.
For research use only. We do not sell to patients.
- CAS No.: 18530-09-1
- Formula: C26H36O8
- Molecular Weight:476.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| KB | IC50 |
10 μg/mL
Compound: 21
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Cytotoxicity against human epidermoid carcinoma KB cells
Cytotoxicity against human epidermoid carcinoma KB cells
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10.1016/S0960-894X(97)00029-2 |
Taxinine A (compound 38) (10 μM; 30 min) shows little to no inhibition of Ca2+-induced depolymerization of purified microtubule protein[1].
Taxinine A epoxidation with meta-chloroperoxybenzoic acid selectively generates the α-4(20)-epoxide in 99% yield, while dimethyldioxirane produces a 2:1 mixture of α- and β-4(20)-epoxides with a 66% overall yield[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 18530-09-1
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Molecular Weight 476.56
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Formula C26H36O8
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SMILES
C[C@@]12[C@](C([C@H](CC2)O)=C)([H])[C@@H]([C@@]3([H])C(C)(C([C@H]([C@@H]1OC(C)=O)OC(C)=O)=C(C(C3)=O)C)C)OC(C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Taxinine A Related Classifications
HY-N18121 Related Classifications
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