2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3819):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N17205
    3''-Hydroxypyrrolezanthine
    3''-Hydroxypyrrolezanthine is a natural alkaloid.
    3''-Hydroxypyrrolezanthine
  • HY-B1502
    21-Acetoxypregnenolone
    21-Acetoxypregnenolone is a derivative of Pregnenolone (HY-B0151) with anti-inflammation activity. 21-Acetoxypregnenolone can be used for rheumatoid arthritis research.
    21-Acetoxypregnenolone
  • HY-122455
    K-102
    K-102 is a small molecule agent that can be used for the study of nervous system diseases, endocrinology and metabolic disease.
    K-102
  • HY-A0137
    Pipotiazine
    Pipotiazine (Pipotiazine) is a Phenothiazine (HY-Y0055) derivative with neuroleptic activity. Pipotiazine (Pipotiazine) can be used for neurological disease research.
    Pipotiazine
  • HY-N8070
    13-O-Cinnamoylbaccatin III
    13-O-Cinnamoylbaccatin III (Baccatin III 13-cinnamate) is a taxane that can be found in the twigs of Taxus mairei.
    13-O-Cinnamoylbaccatin III
  • HY-W392413
    Glutathione monoethyl ester
    Glutathione monoethyl ester is a glutathione derivative that can be transported into cells and hydrolyzed into glutathione. Glutathione monoethyl ester downregulates the gene expression of TEN1 and CTC1 while upregulating TERT expression. Glutathione monoethyl ester enhances telomerase activity, promotes proliferation and differentiation in aged bone marrow stromal cells, while elevating glutathione levels and reducing oxidative stress, protein aggregation and cell death in motor neuronal cells. Glutathione monoethyl ester confers broad multi-organ protection against cerebral ischemia, renal injury, liver damage, and pancreatitis. Glutathione monoethyl ester can be used for the research of amyotrophic lateral sclerosis, stroke, acute renal failure, liver injury, and acute pancreatitis.
    Glutathione monoethyl ester
  • HY-N9749
    Qingyangshengenin 3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside
    Qingyangshengenin 3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside is a natural steroid.
    Qingyangshengenin 3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside
  • HY-147166
    2-Carboxyanthracene MTSEA amide
    2-Carboxyanthracene MTSEA amide is an MTS derivative of anthracene. 2-Carboxyanthracene MTSEA Amide is a special spin-marker.
    2-Carboxyanthracene MTSEA amide
  • HY-N17563
    Morindaparvin A
    Morindaparvin A is a natural product that can be found in Morinda officinalis.
    Morindaparvin A
  • HY-N3467
    Isomexoticin
    Isomexoticin is a natural coumarin.
    Isomexoticin
  • HY-N13837
    2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol
    2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol (Compound 1) is a 9,10-dihydrophenanthrene derivative. 2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol can be isolated from Juncus compressus. 2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol exhibits anticancer activity against cervical and ovarian cancers. 2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol can be used for HSV-2 virus research.
    2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol
  • HY-105178A
    Galarubicin hydrochloride
    Galarubicin hydrochloride (DA 125) is a novel Anthracycline derivative. Galarubicin hydrochloride shows high-affinity DNA binding and topoisomerase II inhibitory activities. Galarubicin hydrochloride induces Apoptosis. Galarubicin hydrochloride exerts cytotoxicity via JNK pathway. Galarubicin hydrochloride can be used in the research of hepatocellular carcinoma.
    Galarubicin hydrochloride
  • HY-N17438
    Myricatomentogenin
    Myricatomentogenin is a diarylheptanoid found in the leaves of Juglans mandshurica.
    Myricatomentogenin
  • HY-N17084
    12β-Hydroxyprogesterone
    12β-Hydroxyprogesterone is a natural steroid.
    12β-Hydroxyprogesterone
  • HY-W614957
    Capecitabine-2',3'-cyclic carbonate
    		98.90%
    Capecitabine-2',3'-cyclic carbonate (Compd 5a) is a 5'-deoxy-5-fluorocytidine derivative with anticancer activity.
    Capecitabine-2',3'-cyclic carbonate
  • HY-N16753
    7-Hydroxyheptaphylline
    7-Hydroxyheptaphylline is a natural alkaloid.
    7-Hydroxyheptaphylline
  • HY-N17035
    Petiolin G
    Petiolin G is a natural phenolic compound.
    Petiolin G
  • HY-118657
    Ripazepam
    Ripazepam (Cl-683) is a potential antianxiety agent. Ripazepam also is a pyrazolodiazepinone derivative and has anxiolytic effects.
    Ripazepam
  • HY-N19847
    LYRM03
    LYRM03 is a derivative of Ubenimex (HY-B0134) and a Aminopeptidase N inhibitor. LYRM03 is isolated from Streptomyces HCCB10043. LYRM03 inhibits TLR4, MyD88, NLRP3, ASC, NF-κB and p38 MAPK, stabilizes IκB, and suppresses LPS-induced expression of iNOS and COX-2. LYRM03 reduces the levels of inflammatory cytokines and oxidative stress markers, and alleviates pulmonary edema. LYRM03 exhibits anticancer activity against breast cancer. LYRM03 has anti-inflammatory activity. LYRM03 can be used in the research of acute lung injury and breast cancer.
    LYRM03
  • HY-119130
    SQ 28516
    SQ 28516 is an active compound.
    SQ 28516