Capecitabine-2',3'-cyclic carbonate
Based on 1 Customer Validation
Capecitabine-2',3'-cyclic carbonate (Compd 5a) is a 5'-deoxy-5-fluorocytidine derivative with anticancer activity.
For research use only. We do not sell to patients.
- Purity: 98.90%
- CAS No.: 921769-65-5
- Formula: C16H20FN3O7
- Molecular Weight:385.34
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
0.08 mg/mL
Compound: 5a
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Cytotoxicity against human HeLa cells after 3 days MTT assay
Cytotoxicity against human HeLa cells after 3 days MTT assay
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[PMID: 22796042] |
| MCF7 | IC50 |
0.08 mg/mL
Compound: 5a
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Cytotoxicity against human MCF7 cells after 3 days MTT assay
Cytotoxicity against human MCF7 cells after 3 days MTT assay
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[PMID: 22796042] |
| NCI-H69 | IC50 |
0.18 mg/mL
Compound: 5a
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Cytotoxicity against human NCI-H69 cells after 3 days MTT assay
Cytotoxicity against human NCI-H69 cells after 3 days MTT assay
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[PMID: 22796042] |
Chemical Information
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CAS No. 921769-65-5
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Appearance Solid
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Molecular Weight 385.34
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Formula C16H20FN3O7
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Color White to off-white
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SMILES
O=C1N(C=C(C(NC(OCCCCC)=O)=N1)F)[C@H]2[C@@]3([H])[C@@](OC(O3)=O)([H])[C@H](O2)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (259.51 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (644 KB)
- English - EN (644 KB)
- Français - FR (644 KB)
- Deutsch - DE (644 KB)
- Norwegian - NO (644 KB)
- Español - ES (644 KB)
- Swedish - SV (644 KB)
- Italian - IT (644 KB)
- Korean - KR (644 KB)
- Portuguese - PT (644 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5951 mL | 12.9756 mL | 25.9511 mL | 64.8778 mL |
| 5 mM | 0.5190 mL | 2.5951 mL | 5.1902 mL | 12.9756 mL | |
| 10 mM | 0.2595 mL | 1.2976 mL | 2.5951 mL | 6.4878 mL | |
| 15 mM | 0.1730 mL | 0.8650 mL | 1.7301 mL | 4.3252 mL | |
| 20 mM | 0.1298 mL | 0.6488 mL | 1.2976 mL | 3.2439 mL | |
| 25 mM | 0.1038 mL | 0.5190 mL | 1.0380 mL | 2.5951 mL | |
| 30 mM | 0.0865 mL | 0.4325 mL | 0.8650 mL | 2.1626 mL | |
| 40 mM | 0.0649 mL | 0.3244 mL | 0.6488 mL | 1.6219 mL | |
| 50 mM | 0.0519 mL | 0.2595 mL | 0.5190 mL | 1.2976 mL | |
| 60 mM | 0.0433 mL | 0.2163 mL | 0.4325 mL | 1.0813 mL | |
| 80 mM | 0.0324 mL | 0.1622 mL | 0.3244 mL | 0.8110 mL | |
| 100 mM | 0.0260 mL | 0.1298 mL | 0.2595 mL | 0.6488 mL |
Capecitabine-2',3'-cyclic carbonate Related Classifications
HY-W614957 Related Classifications
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