2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D0121
    INDO 1
    INDO 1 is a cell-impermeant fluorescent Ca2+ indicator, binds specifically to Ca2+ while emitting fluorescence, the maximum emission wavelength shifts from 485 nm before binding to 410 nm.
    INDO 1
  • HY-D3321
    Streptavidin, R-Phycoerythrin conjugate (SAPE)
    Streptavidin, R-Phycoerythrin conjugate (SAPE) is a streptavidin-labeled phycoerythrin. Streptavidin, R-Phycoerythrin conjugate (SAPE) can be used in conjunction with biotinylated reagents in anti-Biotin/biotin-labeled systems, suitable for flow cytometry detection, microarray analysis, and microplate detection (Ex/Em = 450-500 nm/575 nm).
    Streptavidin, R-Phycoerythrin conjugate (SAPE)
  • HY-D1096
    Sulfo-Cy5 diacid potassium
    Sulfo-Cy5 diacid potassium is a water-soluble, inactive Cy5 carboxylic acid.
    Sulfo-Cy5 diacid potassium
  • HY-D1750
    Rhodamine B thiolactone
    Rhodamine B thiolactone is a high-sensitive Hg2+ indicator used for measuring Hg2+ concentration.
    Rhodamine B thiolactone
  • HY-DY1064
    CY5 (solution)
    CY5 (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance.
    Solvent and concentration: DMSO: 10 mM
    CY5 (solution)
  • HY-132609B
    FAM labled Patisiran sodium
    FAM labled Patisiran sodiumis a FAM labled Patisiran sodium.
    FAM labled Patisiran sodium
  • HY-P2608
    DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH
    DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH is the substrate for matrix metalloproteinase MMP-1, with a Km of 26.61 μM. DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH is utilized as fluorescence probe for detecting protein activity.
    DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH
  • HY-D1183
    Direct blue 67
    Direct blue 67 is a good dyeing agent for cotton fabrics.
    Direct blue 67
  • HY-D3004
    GSH Tracker Probe
    GSH Tracker Probe (CPDSA) is a cyanine-based fluorescent probe with a NIR emission that is specific for GSH (excitation: 635 nm; emission: 655-755 nm). CPDSA can monitor and image GSH levels in live cells and in vivo.
    GSH Tracker Probe
  • HY-D2517
    Cy3-PEG5000-DSPE
    Cy3-PEG5000-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling. Cy3-PEG5000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    Cy3-PEG5000-DSPE
  • HY-D1308
    Sulfo-Cyanine5.5 azide tripotassium
    Sulfo-Cyanine5.5 azide tripotassium, a near-infrared (NIR) fluorescent dye, is an azide-functionalized Sulfo-Cyanine5.5 (Ex=678 nm, Em=694 nm). Sulfo-Cyanine5.5 azide tripotassium can react with alkynes for Click Chemistry labeling. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Sulfo-Cyanine5.5 azide tripotassium
  • HY-P11367
    Boc-Ala-Gly-Pro-Arg-AMC
    Boc-Ala-Gly-Pro-Arg-AMC is a synthetic fluorescent substrate, widely used for the detection of protease activity. Boc-Ala-Gly-Pro-Arg-AMC can be used to detect the activity of serine proteases and the oligopeptide enzyme B of Trypanosoma brucei.
    Boc-Ala-Gly-Pro-Arg-AMC
  • HY-P4400
    Z-VDVAD-AFC
    Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals.
    Z-VDVAD-AFC
  • HY-D2238
    Disulfo-ICG-NHS disodium
    Disulfo-ICG-NHS disodium is a fluorescent dye.
    Disulfo-ICG-NHS disodium
  • HY-D3048E
    Rhodamine B-Chitosan (MW 100000)
    Rhodamine B-Chitosan (MW 100000) is a Rhodamine B (HY-Y0016)-labeled chitosan with a molecular weight of 100,000. Rhodamine B-Chitosan (MW 100000) combines the polysaccharide properties of chitosan with the fluorescence properties of Rhodamine B, playing an important role in fields such as fluorescent labeling, cell imaging, and drug delivery research (Ex/Em = 546/610 nm).
    Rhodamine B-Chitosan (MW 100000)
  • HY-P3791
    N-Succinyl-Ile-Ile-Trp-AMC
    N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY).
    N-Succinyl-Ile-Ile-Trp-AMC
  • HY-D1472
    Azure A eosinate
    Azure A eosinate is a dye for hematological and histological applications. Azure A eosinate can be used as new photosensitizer prototypes to determine growth inhibition of Candida albicans.
    Azure A eosinate
  • HY-D3170
    C-HBrO-GGT
    C-HBrO-GGT is a sequence-activated two-photon fluorescent probe. C-HBrO-GGT exhibits sequential fluorescence activation properties: it generates fluorescence in response to hypobromous acid only after being hydrolytically activated by γ-glutamyl transpeptidase. C-HBrO-GGT enables verification of the voltage-gated chloride channel (CLC-1)-HBrO-catalase (CAT)-GGT signaling pathway at the cellular level. C-HBrO-GGT can serve as a tool to indicate the precise location of mature atherosclerotic plaques and provide early warning of plaque formation. C-HBrO-GGT is applicable to relevant research on atherosclerosis.
    C-HBrO-GGT
  • HY-D1461
    Fluorescein Di-β-D-Glucopyranoside
    Fluorescein Di-β-D-Glucopyranoside is a specific β-glucocerebrosidase substrate that can be used for the intralysosomal β-galactosidase.
    Fluorescein Di-β-D-Glucopyranoside
  • HY-D2889A
    RB-PEG600-Biotin
    RB-PEG600-Biotin (Rhodamine B-PEG600-Biotin) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. RB-PEG600-Biotin plays an important role in the specific capture and detection of biomolecules (Ex/Em=546/610 nm).
    RB-PEG600-Biotin
Cat. No. Product Name / Synonyms Application Reactivity