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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D2836J
    FITC-HA (MW 3000)
    FITC-HA (MW 3000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM).
    FITC-HA (MW 3000)
  • HY-D2136
    Cy3-PEG2-Azide
    Cy3-PEG2-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 2 PEG units. Cy3-PEG2-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Cy3-PEG2-Azide
  • HY-126821
    Fluo-3
    Fluo-3 is a cell-impermeable calcium ion (Ca2+) indicator. Fluo-3 itself is not fluorescent, but it becomes fluorescent after binding to calcium ions (Ex/Em = 488/525 nm).
    Fluo-3
  • HY-D3172
    BD-105
    BD-105 is a glucagon-binding fluorescent probe with a Ka value of 13.3 μM. BD-105 exhibits changes in fluorescence intensity upon interaction with glucagon, and colocalizes with glucagon in cells and tissues. BD-105 is a selective cell stain that labels glucagon-secreting cells without staining insulin-secreting cells or non-endocrine control cells. BD-105 serves as an imaging reagent for glucagon in live cells and tissues.
    BD-105
  • HY-D2077
    ATTO 725 azide
    ATTO 725 azide is an azide derivative of ATTO 725 with excitation/emission maxima at 728/751 nm. ATTO 725 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    ATTO 725 azide
  • HY-132590D
    FAM labled Revusiran sodium
    FAM labled Revusiran sodiumis a FAM labled Revusiran sodium.
    FAM labled Revusiran sodium
  • HY-D2952
    BOCA-1-BG
    BOCA-1-BG is a BODIPY-labeled SNAP tag fluorescence probe. BOCA-1-BG can be used to detect Ca2+ concentration and serves as a highly sensitive Ca2+ fluorescent indicator.
    BOCA-1-BG
  • HY-163286
    BODIQPy-TPA
    BODIQPy-TPA is a lipophilic probes, which induces ferroptosis in B16 and HepG2 cells upon light irradiation through lipid peroxidation. BODIQPy-TPA reveals a maximum absorption wavelength of 488 nm and a maximum emission wavelength above 640 nm.
    BODIQPy-TPA
  • HY-D1924
    ATTO 390 alkyne
    ATTO 390 alkyne is an alkyne derivative of ATTO 390 with maximum excitation/emission wavelengths: 390/476 nm. ATTO 390 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    ATTO 390 alkyne
  • HY-179330
    PSMA-1092
    PSMA-1092 is a fluorescence probe targeting prostate-specific membrane antigen (PSMA) with a Ki of 80 pM. PSMA-1092 can be used for tumor localization and imaging, such as prostate cancer.
    PSMA-1092
  • HY-132611D
    FAM labled Golodirsen sodium
    FAM labled Golodirsen sodiumis a FAM labled Golodirsen sodium.
    FAM labled Golodirsen sodium
  • HY-D2800D
    FITC-PEG10000-MAL
    FITC-PEG10000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG10000-MAL can be used for fluorescent labeling and imaging.
    FITC-PEG10000-MAL
  • HY-D1949
    ATTO 594 streptavidin
    ATTO 594 Streptavidin is a streptavidin derivative of ATTO 594, it can label protein or antibody, the maximum excitation/emission wavelength: 603/626 nm.
    ATTO 594 streptavidin
  • HY-P4416
    Ac-Gly-Ala-Lys(Ac)-AMC
    Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Gly-Ala-Lys(Ac)-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal.
    Ac-Gly-Ala-Lys(Ac)-AMC
  • HY-D1578
    C12FDGlcU
    C12FDGlcU is a lipophilic analog of fluorescein di-β-D-glucuronic acid. C12FDGlcU can be useful for the detection of β-glucuronidase (GUS) gene expression. C12FDGlcU can enter the cells and then be cleaved by β-glucuronidase, generating the yellow-colored, green-fluorescent fluorescein (Abs/Em of the reaction product: 495/518 nm).
    C12FDGlcU
  • HY-132608B
    FAM labled Inotersen sodium
    FAM labled Inotersen sodiumis a FAM labled Inotersen sodium.
    FAM labled Inotersen sodium
  • HY-D0094
    2-Ethoxy-2-(2-naphthyl)ethanenitril
    2-Ethoxy-2-(2-naphthyl)ethanenitril is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    2-Ethoxy-2-(2-naphthyl)ethanenitril
  • HY-D3394
    SGC5
    SGC5 is a fluorescence enhancer and membrane dissociator with millisecond-scale membrane dissociation kinetics, with an emission spectrum of 500-650 nm. SGC5 produces strong fluorescence upon binding to lipid membranes, exhibits fast partitioning dissociation kinetics at higher temperatures, and is unaffected by pH or cholesterol. SGC5 does not belong to the FM dye family and shows the highest membrane-bound fluorescence intensity among the tested styryl/FM dyes. SGC5 can be used to study synaptic vesicle cycling in neurons.
    SGC5
  • HY-129097
    FFN-102 trifluoroacetate
    FFN-102 trifluoroacetate is an analogue of biogenic neurotransmitters. FFN-102 trifluoroacetate is a pH-dependent fluorescent probe that labels dopamine cell bodies, axons, and presynaptic terminals.
    FFN-102 trifluoroacetate
  • HY-D2944
    SNAP-649
    SNAP-649 is a DY-649P1-labeled SNAP tag fluorescent probe.
    SNAP-649
Cat. No. Product Name / Synonyms Application Reactivity