2. Others Apoptosis
  3. Fluorescent Dye Ferroptosis
  4. BODIQPy-TPA

BODIQPy-TPA is a lipophilic probes, which induces ferroptosis in B16 and HepG2 cells upon light irradiation through lipid peroxidation. BODIQPy-TPA reveals a maximum absorption wavelength of 488 nm and a maximum emission wavelength above 640 nm.

For research use only. We do not sell to patients.

BODIQPy-TPA Chemical Structure

BODIQPy-TPA Chemical Structure

CAS No. : 2738333-02-1

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BODIQPy-TPA Related Antibodies

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Description

BODIQPy-TPA is a lipophilic probes, which induces ferroptosis in B16 and HepG2 cells upon light irradiation through lipid peroxidation. BODIQPy-TPA reveals a maximum absorption wavelength of 488 nm and a maximum emission wavelength above 640 nm[1].

In Vitro

BODIQPy-TPA (5 μM) ferrostatin-dependently reveals photocytotoxicity with IC50 of 0.51 μM in B16 cells under blue LED irradiation, downregulates expression of ferritin heavy polypeptide 1 (FTH1) [1].
BODIQPy-TPA (5 μM) increases levels of triacylglycerol (TG) and downregulates phosphatidylcholine (PC) with light irradiation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

BODIQPy-TPA Related Antibodies

Cell Viability Assay[1]

Cell Line: B16
Concentration: 0-50 μM
Incubation Time: 48 h
Result: Inhibited B16 cells viability, decreased the cytotoxicity with presence of ferrostatin.

Western Blot Analysis[1]

Cell Line: B16
Concentration: 5 μM
Incubation Time: 48 h
Result: Decreased levels of FTH1.
Molecular Weight

540.37

Formula

C33H23BF2N4O
CAS No.
SMILES

[F-][B+3]1([N-]2C(C3=CC(/C=C/C4=CC=C(C=C4)N(C5=CC=CC=C5)C6=CC=CC=C6)=CC=[N]31)=NC7=CC=CC=C7C2=O)[F-]
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BODIQPy-TPA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BODIQPy-TPA2738333-02-1Fluorescent DyeFerroptosisFerrostatinB16HepG2ferroptosisphotocytotoxicperoxidationInhibitorinhibitorinhibit

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