BODIQPy-TPA
BODIQPy-TPA is a lipophilic probes, which induces ferroptosis in B16 and HepG2 cells upon light irradiation through lipid peroxidation. BODIQPy-TPA reveals a maximum absorption wavelength of 488 nm and a maximum emission wavelength above 640 nm.
For research use only. We do not sell to patients.
- CAS No.: 2738333-02-1
- Formula: C33H23BF2N4O
- Molecular Weight:540.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
BODIQPy-TPA (5 μM) ferrostatin-dependently reveals photocytotoxicity with IC50 of 0.51 μM in B16 cells under blue LED irradiation, downregulates expression of ferritin heavy polypeptide 1 (FTH1) [1].
BODIQPy-TPA (5 μM) increases levels of triacylglycerol (TG) and downregulates phosphatidylcholine (PC) with light irradiation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2738333-02-1
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Molecular Weight 540.37
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Formula C33H23BF2N4O
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SMILES
[F-][B+3]1([N-]2C(C3=CC(/C=C/C4=CC=C(C=C4)N(C5=CC=CC=C5)C6=CC=CC=C6)=CC=[N]31)=NC7=CC=CC=C7C2=O)[F-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)