2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10875):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W770410
    9-PAHSA-13C4
    		99.9%
    9-PAHSA-13C4 is 13C-labeled 9-PAHSA. 9-PAHSAis an orally active endogenous GPR120 agonist (EC50=18 μM). 9-PAHSAsignificantly inhibits LPS-induced inflammatory responses by blocking the NF-κB pathway. 9-PAHSAinduces adipocyte browning, enhances glucose uptake and reduces lipid accumulation, while improving mitochondrial function and the survival rate of steatotic hepatocytes. In terms of neuroprotection, 9-PAHSAregulates the expression of REST and BDNF in the prefrontal cortex of diabetic mice, and effectively prevents spatial working memory deficits and abnormal social behaviors. 9-PAHSAdoes not directly regulate insulin secretion or improve systemic insulin sensitivity, and possesses specific anti-inflammatory, metabolic regulatory and neuroprotective properties. 9-PAHSAcan be used in the research of diabetes-related cognitive impairment, obesity and non-alcoholic fatty liver disease.
    9-PAHSA-<sup>13</sup>C<sub>4</sub>
  • HY-146627S
    5-Cholesten-24(RS)-methyl-3β-ol-d3
    		99.21%
    5-Cholesten-24(RS)-methyl-3β-ol-d3 is the deuterium labeled 5-Cholesten-24(RS)-methyl-3β-ol.
    5-Cholesten-24(RS)-methyl-3β-ol-d<sub>3</sub>
  • HY-159064S
    DSPSAPVNVT(Val-13C5,15N)R TFA
    DSPSAPVNVT(Val-13C5,15N)R TFA is the 13C and 15N-labeled DSPSAPVNVT(Val)R.
    DSPSAPVNVT(Val-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N)R TFA
  • HY-B1773AS4
    Sodium propionate-d5
    		99.91%
    Sodium propionate-d5 is the deuterium labeled Propionate sodium (HY-B1773A). Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease.
    Sodium propionate-d<sub>5</sub>
  • HY-146840S
    17:0-14:1 PC-d5
    		≥99.0%
    17:0-14:1 PC-d5 is deuterium labeled 17:0-14:1 PC.
    17:0-14:1 PC-d<sub>5</sub>
  • HY-10570S1
    Nevirapine-d3
    		99.62%
    Nevirapine-d3 (BI-RG 587-d3) is the deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM.
    Nevirapine-d<sub>3</sub>
  • HY-Y0203S
    2,4-Dichloropyrimidine-d2
    		99.32%
    2,4-Dichloropyrimidine-d2 is the deuterium labeled 2,4-Dichloropyrimidine. 2,4-Dichloropyrimidine is a sensitizer.
    2,4-Dichloropyrimidine-d<sub>2</sub>
  • HY-126474S
    MitoB-d15 bromide
    MitoB-d15 (bromide) is deuterium labeled MitoB (bromide). MitoB bromide is an exomarker of mitochondrial hydrogen peroxide. MitoB bromide is a mitochondria-targeted ratiometric probe, and can be used to measure levels of one major ROS, hydrogen peroxide, within living animals.
    MitoB-d<sub>15</sub> bromide
  • HY-B0317AS
    Amlodipine-d4 maleate
    		98.19%
    Amlodipine-d4 (maleate) is the deuterium labeled Amlodipine maleate. Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent. Amlodipine maleate blocks the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine maleate can be used for the research of high blood pressure and cancer.
    Amlodipine-d<sub>4</sub> maleate
  • HY-W128417S
    4-(Dimethylamino)phenacyl bromide-13C2,d6
    		98.14%
    4-(Dimethylamino)phenacyl bromide-13C2,d6 (DmPABr-13C2,d6) is 13C-labeled 4-(Dimethylamino)phenacyl bromide (HY-W128417).
    4-(Dimethylamino)phenacyl bromide-<sup>13</sup>C<sub>2</sub>,d<sub>6</sub>
  • HY-W653994
    Ethyl Paraben-13C6
    		99.65%
    Ethyl Paraben-13C6 (Ethyl parahydroxybenzoate-13C6) is 13C labeled Ethylparaben. Ethylparaben is the ethyl ester of paraben and is used as an antifungal preservative and food additive.
    Ethyl Paraben-<sup>13</sup>C<sub>6</sub>
  • HY-B0212S
    Sulfapyridine-d4
    		99.35%
    Sulfapyridine-d4 a deuterium labeled Sulfapyridine. Sulfapyridine is a sulfonamide antibacterial.
    Sulfapyridine-d<sub>4</sub>
  • HY-W015301S1
    Dimethyl adipate-d4-1
    		99.40%
    Dimethyl adipate-d4-1 (Hexanedioic acid dimethyl ester-d4-1) is the deuterium labeled Dimethyl adipate (HY-W015301). Dimethyl adipate is an aliphatic dicarboxylate compound. Dimethyl adipate is mainly used as a plasticizer and an intermediate in organic synthesis.
    Dimethyl adipate-d<sub>4</sub>-1
  • HY-N0215S
    L-Phenylalanine-d7
    		99.90%
    L-Phenylalanine-d7 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.
    L-Phenylalanine-d<sub>7</sub>
  • HY-163163S
    18:1-21:2-18:1 TG-d5
    		99.00%
    18:1-21:2-18:1 TG-d5 is deuterium labeled 18:1-21:2-18:1 TG.
    18:1-21:2-18:1 TG-d<sub>5</sub>
  • HY-W654243
    Isovalerylcarnitine-d9-1 chloride
    		99.55%
    Isovalerylcarnitine-d9-1 (chloride) is deuterium labeled Isovalerylcarnitine (chloride). Isovalerylcarnitine chloride, a product of the catabolism of L-leucine, is a potent activator of the Ca2+-dependent proteinase (calpain) of human neutrophils.
    Isovalerylcarnitine-d<sub>9</sub>-1 chloride
  • HY-W012278S
    Benz[a]anthracene-d12
    		99.74%
    Benz[a]anthracene-d12 is the deuterium labeled Benz[a]anthracene.
    Benz[a]anthracene-d<sub>12</sub>
  • HY-W077074S
    1-Ethyl-1H-pyrazole-5-carboxylic acid-d5
    1-Ethyl-1H-pyrazole-5-carboxylic acid-d5 is the deuterium labeled 1-Ethyl-1H-pyrazole-5-carboxylic acid (HY-W077074).
    1-Ethyl-1H-pyrazole-5-carboxylic acid-d<sub>5</sub>
  • HY-113331S
    Thromboxane B2-d4
    		99.9%
    Thromboxane B2-D4 is the deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation.
    Thromboxane B2-d<sub>4</sub>
  • HY-128922S
    Dexamethasone palmitate-d31
    		99.31%
    Dexamethasone palmitate-d31 is the deuterium labeled Dexamethasone palmitate(HY-128922).Dexamethasone palmitate (DXP) is a proagent of Dexamethasone (HY-14648). Dexamethasone palmitate can be used for the research of inflammation.
    Dexamethasone palmitate-d<sub>31</sub>