Isovalerylcarnitine-d9-1 chloride
Based on 1 Customer Validation
Isovalerylcarnitine-d9-1 (chloride) is deuterium labeled Isovalerylcarnitine (chloride). Isovalerylcarnitine chloride, a product of the catabolism of L-leucine, is a potent activator of the Ca2+-dependent proteinase (calpain) of human neutrophils.
For research use only. We do not sell to patients.
- Purity: 99.55%
- Formula: C12H15D9ClNO4
- Molecular Weight:290.83
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 139144-12-0
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Appearance Solid
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Molecular Weight 290.83
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Formula C12H15D9ClNO4
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Color White to light yellow
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SMILES
O=C(O[C@H](CC(O)=O)C[N+](C)(C)C)C([2H])(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])[2H].[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (343.84 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Pontremoli S, et al. Isovalerylcarnitine is a specific activator of calpain of human neutrophils. Biochem Biophys Res Commun. 1987 Nov 13;148(3):1189-95. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4384 mL | 17.1922 mL | 34.3843 mL | 85.9609 mL |
| 5 mM | 0.6877 mL | 3.4384 mL | 6.8769 mL | 17.1922 mL | |
| 10 mM | 0.3438 mL | 1.7192 mL | 3.4384 mL | 8.5961 mL | |
| 15 mM | 0.2292 mL | 1.1461 mL | 2.2923 mL | 5.7307 mL | |
| 20 mM | 0.1719 mL | 0.8596 mL | 1.7192 mL | 4.2980 mL | |
| 25 mM | 0.1375 mL | 0.6877 mL | 1.3754 mL | 3.4384 mL | |
| 30 mM | 0.1146 mL | 0.5731 mL | 1.1461 mL | 2.8654 mL | |
| 40 mM | 0.0860 mL | 0.4298 mL | 0.8596 mL | 2.1490 mL | |
| 50 mM | 0.0688 mL | 0.3438 mL | 0.6877 mL | 1.7192 mL | |
| 60 mM | 0.0573 mL | 0.2865 mL | 0.5731 mL | 1.4327 mL | |
| 80 mM | 0.0430 mL | 0.2149 mL | 0.4298 mL | 1.0745 mL | |
| 100 mM | 0.0344 mL | 0.1719 mL | 0.3438 mL | 0.8596 mL |
Isovalerylcarnitine-d9-1 chloride Related Classifications
HY-W654243 Related Classifications
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