Isovalerylcarnitine-d₉-1 chloride

Cat. No.: HY-W654243 Purity: 99.55%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Isovalerylcarnitine-d₉-1 (chloride) is deuterium labeled Isovalerylcarnitine (chloride). Isovalerylcarnitine chloride, a product of the catabolism of L-leucine, is a potent activator of the Ca²⁺-dependent proteinase (calpain) of human neutrophils.

For research use only. We do not sell to patients.

Isovalerylcarnitine-d<sub>9</sub>-1 chloride

Isovalerylcarnitine-d₉-1 chloride Chemical Structure

Size	Stock	Quantity
1 mg	Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
5 mg	Get quote
10 mg	Get quote

Synthetic products have potential research and development risk.

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Isovalerylcarnitine-d₉-1 chloride:

Isovalerylcarnitine chloride In-stock

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All Endogenous Metabolite Isoform Specific Products:

View All Isoforms

Human Endogenous Metabolite Microbial Metabolite

Biological Activity
Purity & Documentation
References
Customer Review

Description

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Molecular Weight

290.83

Formula

C₁₂H₁₅D₉ClNO₄

Unlabeled CAS

139144-12-0

Appearance

Solid

Color

White to light yellow

SMILES

O=C(O[C@H](CC(O)=O)C[N+](C)(C)C)C([2H])(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])[2H].[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (343.84 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4384 mL	17.1922 mL	34.3843 mL
5 mM	0.6877 mL	3.4384 mL	6.8769 mL
10 mM	0.3438 mL	1.7192 mL	3.4384 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.55%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (255 KB) Elemental Analysis Report (113 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Pontremoli S, et al. Isovalerylcarnitine is a specific activator of calpain of human neutrophils. Biochem Biophys Res Commun. 1987 Nov 13;148(3):1189-95. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.4384 mL	17.1922 mL	34.3843 mL	85.9609 mL
	5 mM	0.6877 mL	3.4384 mL	6.8769 mL	17.1922 mL
	10 mM	0.3438 mL	1.7192 mL	3.4384 mL	8.5961 mL
	15 mM	0.2292 mL	1.1461 mL	2.2923 mL	5.7307 mL
	20 mM	0.1719 mL	0.8596 mL	1.7192 mL	4.2980 mL
	25 mM	0.1375 mL	0.6877 mL	1.3754 mL	3.4384 mL
	30 mM	0.1146 mL	0.5731 mL	1.1461 mL	2.8654 mL
	40 mM	0.0860 mL	0.4298 mL	0.8596 mL	2.1490 mL
	50 mM	0.0688 mL	0.3438 mL	0.6877 mL	1.7192 mL
	60 mM	0.0573 mL	0.2865 mL	0.5731 mL	1.4327 mL
	80 mM	0.0430 mL	0.2149 mL	0.4298 mL	1.0745 mL
	100 mM	0.0344 mL	0.1719 mL	0.3438 mL	0.8596 mL