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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10875):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-151892S
    Glimepiride-d4(phenylethyl-α,α,β,β-d4)(cis/trans)
    Glimepiride-d4(phenylethyl-α,α,β,β-d4)(cis/trans) is the deuterium labeled .
    Glimepiride-d<sub>4</sub>(phenylethyl-α,α,β,β-d<sub>4</sub>)(cis/trans)
  • HY-W710272
    2-(Dimethylamino)acetanilide-d6
    2-(Dimethylamino)acetanilide-d6 is the deuterium labeled 2-(Dimethylamino)acetanilide.
    2-(Dimethylamino)acetanilide-d<sub>6</sub>
  • HY-W702852
    4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane-d5
    4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane-d5 (5-bromomethyl-2,2-dimethyl-1,3-dioxolane-d5) is the deuterium labeled 4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane (HY-W018073).
    4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane-d<sub>5</sub>
  • HY-12773AS
    5-Hydroxy Propafenone-d5 hydrochloride
    5-Hydroxy Propafenone-d5 (hydrochloride) is the deuterium labeled 5-Hydroxy Propafenone.
    5-Hydroxy Propafenone-d<sub>5</sub> hydrochloride
  • HY-W012990S
    Piperidin-3-ol-d9
    Piperidin-3-ol-d9 is a deuterated labeled Piperidin-3-ol.
    Piperidin-3-ol-d<sub>9</sub>
  • HY-W745009
    N-Demethyl-N-formylolanzapine-d8
    N-Demethyl-N-formylolanzapine-d8 is the deuterium labeled N-Demethyl-N-formylolanzapine.
    N-Demethyl-N-formylolanzapine-d<sub>8</sub>
  • HY-131414S5
    N-Demethyl vandetanib-d5
    N-Demethyl vandetanib-d5 is the deuterium labeled N-Demethyl Vandetanib (HY-131414).
    N-Demethyl vandetanib-d<sub>5</sub>
  • HY-W756792
    1H,1H,2H,2H-Perfluorodecanesulfonic acid-13C2 sodium
    1H,1H,2H,2H-Perfluorodecanesulfonic acid-13C2 sodium is the 13C-labeled 1H,1H,2H,2H-Perfluorodecanesulfonic acid sodium.
    1H,1H,2H,2H-Perfluorodecanesulfonic acid-<sup>13</sup>C<sub>2</sub> sodium
  • HY-19489S4
    (±)-Levomepromazine-13C,d3
    (±)-Levomepromazine-13C,d3 ((±)-Methotrimeprazine-13C,d3) is the deuterium and 13C-labeled (±)-Levomepromazine (HY-19489). (±)-Levomepromazine ((±)-Methotrimeprazine) is the racemate of Levomepromazine (HY-B1693).
    (±)-Levomepromazine-<sup>13</sup>C,d<sub>3</sub>
  • HY-19568S
    Peficitinib-d3
    Peficitinib-d3 (ASP015K-d3) is the deuterium labeled Peficitinib (HY-19568). Peficitinib (ASP015K) is an orally active JAK inhibitor, with IC50s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively.
    Peficitinib-d<sub>3</sub>
  • HY-P2625S1
    GLP-2(3-33) (Leu-13C6,15NN) TFA
    GLP-2(3-33) (Leu-13C6,15N) TFA is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
    GLP-2(3-33) (Leu-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>NN) TFA
  • HY-146869S
    1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d5 sodium
    1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d5 (sodium) is deuterium labeled 1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine (sodium).
    1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d<sub>5</sub> sodium
  • HY-128753S6
    D-Lyxose-d
    D-Lyxose-d is the deuterium labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose.
    D-Lyxose-d
  • HY-W745905
    2'-Deoxyadenosine-15N1
    2'-Deoxyadenosine-15N1 is the 15N-labeled 2'-Deoxyadenosine (HY-W040329). 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer.
    2'-Deoxyadenosine-<sup>15</sup>N<sub>1</sub>
  • HY-W751343
    Perfluoro-n-tetradecanoic acid-13C2
    Perfluoro-n-tetradecanoic acid-13C2 (PFTeDA-13C2) is the 13C-labeled Perfluoro-n-tetradecanoic acid.
    Perfluoro-n-tetradecanoic acid-<sup>13</sup>C<sub>2</sub>
  • HY-113232S
    3-Methylcrotonylglycine-d2
    3-Methylcrotonylglycine-d2 is the deuterium labeled 3-Methylcrotonylglycine. 3-Methylcrotonylglycine is an acyl glycine, a normal amino acid metabolite found in urine.
    3-Methylcrotonylglycine-d<sub>2</sub>
  • HY-W777297
    Lapatinib-13C215N
    Lapatinib-13C2,15N Ditosylate is the 13C- and 15N-labeled Lapatinib ditosylate (HY-50898A). Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.
    Lapatinib-<sup>13</sup>C<sub>2</sub>15</sup>N</sub>
  • HY-W268193S
    Dansyl acid-d6
    Dansyl acid-d6 is the deuterium labeled Propan-2-amine hydrochloride.
    Dansyl acid-d<sub>6</sub>
  • HY-145149S
    Duostatin 5-13C,d3
    Duostatin 5-13C,d3 is the 13C-labeled Duostatin 5 (HY-145149). Duostatin 5 is a ADC Cytotoxin designed based on MMAF (HY-15579) and can be used to synthesize ADCs. The preparation of Duostatin 5 has the advantages of fewer synthetic steps, simple operation, less difficulty in quality control, and more stable chemical synthesis process. Duostatin 5 can be linked to the antibody targeting 5T4 (ZV05) by cross-linking with interchain cysteines through a disubstituted C-Lock linker. Duostatin 5 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups[1][2].
    Duostatin 5-<sup>13</sup>C,d<sub>3</sub>
  • HY-14284S
    Nilvadipine-d4
    Nilvadipine-d4 is deuterium labeled Nilvadipine. Nilvadipine is a potent calcium channel antagonist, and the IC50 value is around 0.1 nM.
    Nilvadipine-d<sub>4</sub>