Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds 関連製品 (10875):

製品番号	製品名	製品効果	純度	構造式

HY-146870S

1-Heptadecanoyl-2-myristoleoyl-sn-glycero-3-phospho- L-serine-d₅ sodium
1-Heptadecanoyl-2-myristoleoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-myristoleoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-W653885

rac 3,4-Dihydroxymandelic Acid-d₃
rac 3,4-Dihydroxymandelic Acid-d₃ is deuterium labeled 3,4-Dihydroxymandelic acid. 3,4-Dihydroxymandelic acid is a metabolite of norepinephrine.

HY-W709340

N-Boc-S-Bzl-L-Cys-Gly-OBzl-¹³C₂,¹⁵N
N-Boc-S-Bzl-L-Cys-Gly-OBzl-¹³C₂,¹⁵N (Benzyl S-benzyl-N-(tert-butoxycarbonyl)-L-cysteinylglycinate-¹³C₂,¹⁵N) is the ¹³C- and ¹⁵N-labeled Benzyl S-benzyl-N-(tert-butoxycarbonyl)-L-cysteinylglycinate (HY-W699579).

HY-W782193

Sulcatone-d₅
Sulcatone-d₅ (6-Methyl-5-hepten-2-one-d₅) is the deuterium labeled Sulcatone (HY-W010435). Sulcatone (6-Methyl-5-hepten-2-one) is a plant-derived volatile organic compound with activities such as insecticidal, antifungal, and blood pressure-lowering effects. Sulcatone also serves as an insect pheromone and an endogenous metabolite, which can be found in feces. Changes in Sulcatone levels can be used for the auxiliary diagnosis of ulcerative colitis.

HY-143786S

Tazobactum ester-¹³C,d₃
Tazobactum ester-¹³C,d₃ is the deuterium and ¹³C labeled Tazobactum ester.

HY-B0161AS1

Duloxetine-d₇ hydrochloride
Duloxetine-d7 hydrochloride ((S)-Duloxetine-d7 hydrochloride) is the deuterium labeled Duloxetine hydrochloride (HY-B0161A). Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a K_i of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).

HY-172425

Deulumateperone
Deulumateperone is a deuterium labeled Lumateperone (HY-17637). Lumateperone is the orally active 5-HT2A receptor antagonist (K_i = 0.54 nM) and the modulator for dopamine receptor that exhibits antipsychotic and antineoplastic activities.

HY-157541S

2-Chloro-1,3-propanediol-¹³C₃
2-Chloro-1,3-propanediol-¹³C₃ is the ¹³C-labeled 2-Chloro-1,3-propanediol. 2-Chloro-1,3-propanediol is an ester product.

HY-A0031S

Bazedoxifene-d₄
Bazedoxifene-d₄ is deuterium labeled Bazedoxifene. Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene can be used for the research of osteoporosis. Bazedoxifene also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer[1][2].

HY-W150053S

N-Octyl 4-hydroxybenzoate-d₄
N-Octyl 4-hydroxybenzoate-d₄ is the deuterium labeled N-Octyl 4-hydroxybenzoate.

HY-113400S2

Cytidine diphosphate-¹³C₉,¹⁵N₃ dilithium		99.7%
Cytidine diphosphate-¹³C₉,¹⁵N₃ dilithium is ¹³C and ¹⁵N-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-66005S3

Acetaminophen-¹³C₆
Acetaminophen-13C6 (Paracetamol-13C6) is the 13C-labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC₅₀ of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

HY-N0650S4

L-Serine-2-¹³C		99.71%
L-Serine-2-¹³C is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-W705545

Tri-n-octyl trimellitate-d₅₁
Tri-n-octyl trimellitate-d₅1 is the deuterium labeled Tri-n-octyl trimellitate.

HY-116956S1

D-Erythrose-2-¹³C
D-Erythrose-2-¹³C is the ¹³C labeled D-Erythrose.

HY-113369S

Cholesteryl arachidonate-d₈
Cholesteryl arachidonate-d₈ is deuterium labeled Cholesteryl arachidonate (HY-113369). Cholesteryl arachidonate, a lipid, is an endogenous metabolite. Cholesteryl arachidonate has antibacterial activity.

HY-166903S

2,3,4,5-Tetrachlorodiphenyl ether-¹³C₁₂
2,3,4,5-Tetrachlorodiphenyl ether-¹³C₁₂ is ¹³C labeled 2,3,4,5-Tetrachlorodiphenyl ether.

HY-14252S

Milrinone-d₃
Milrinone-d₃ is deuterium labeled Milrinone. Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator.

HY-10330S

Toceranib-d₈		99.08%
Toceranib-d₈ is the deuterium labeled Toceranib. Toceranib (SU11654) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib (SU11654) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors.

HY-W718706

(R)-2-Acetamidobutanoic acid-d₅
(R)-2-Acetamidobutanoic acid-d₅ (Acetyl-D-2-aminobutyric acid-d₅) is the deuterium labeled (R)-2-Acetamidobutanoic acid (HY-W101286).

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