rac 3,4-Dihydroxymandelic Acid-d3
Based on 1 Customer Validation
rac 3,4-Dihydroxymandelic Acid-d3 is deuterium labeled 3,4-Dihydroxymandelic acid. 3,4-Dihydroxymandelic acid is a metabolite of norepinephrine.
For research use only. We do not sell to patients.
- Formula: C8H5D3O5
- Molecular Weight:187.16
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
More
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled Cas 775-01-9
-
Molecular Weight 187.16
-
Formula C8H5D3O5
-
SMILES
OC1=C(C([2H])=C(C([2H])=C1O)C(C(O)=O)O)[2H]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
DMSO : 83.33 mg/mL (445.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Sule N, et al. The Norepinephrine Metabolite 3,4-Dihydroxymandelic Acid Is Produced by the Commensal Microbiota and Promotes Chemotaxis and Virulence Gene Expression in Enterohemorrhagic Escherichia coli. Infect Immun. 2017 Sep 20;85(10). [Content Brief]
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.3430 mL | 26.7151 mL | 53.4302 mL | 133.5755 mL |
| 5 mM | 1.0686 mL | 5.3430 mL | 10.6860 mL | 26.7151 mL | |
| 10 mM | 0.5343 mL | 2.6715 mL | 5.3430 mL | 13.3576 mL | |
| 15 mM | 0.3562 mL | 1.7810 mL | 3.5620 mL | 8.9050 mL | |
| 20 mM | 0.2672 mL | 1.3358 mL | 2.6715 mL | 6.6788 mL | |
| 25 mM | 0.2137 mL | 1.0686 mL | 2.1372 mL | 5.3430 mL | |
| 30 mM | 0.1781 mL | 0.8905 mL | 1.7810 mL | 4.4525 mL | |
| 40 mM | 0.1336 mL | 0.6679 mL | 1.3358 mL | 3.3394 mL | |
| 50 mM | 0.1069 mL | 0.5343 mL | 1.0686 mL | 2.6715 mL | |
| 60 mM | 0.0891 mL | 0.4453 mL | 0.8905 mL | 2.2263 mL | |
| 80 mM | 0.0668 mL | 0.3339 mL | 0.6679 mL | 1.6697 mL | |
| 100 mM | 0.0534 mL | 0.2672 mL | 0.5343 mL | 1.3358 mL |