Cholesteryl arachidonate-d₈ 

Cholesteryl arachidonate-d₈ is deuterium labeled Cholesteryl arachidonate (HY-113369). Cholesteryl arachidonate, a lipid, is an endogenous metabolite. Cholesteryl arachidonate has antibacterial activity^[1][2][3].

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon and other elements have been incorporated into drug molecules, mainly serving as quantitative tracers in drug development. Deuteration has drawn attention for its potential impact on the pharmacokinetic and metabolic properties of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

681.15

C₄₇H₆₈D₈O₂

604-34-2

C[C@@]12C(C[C@H](CC1)OC(CCC/C([2H])=C(C/C([2H])=C(C/C([2H])=C(C/C([2H])=C(CCCCC)/[2H])/[2H])/[2H])/[2H])=O)=CC[C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@]4([H])[C@H](C)CCCC(C)C)[H])C)[H])[H]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Holub B J, et al. Interrelationships in the metabolism of liver arachidonoyllecithins and plasma cholesteryl arachidonate in the rat[J]. Canadian Journal of Biochemistry, 1971, 49(9): 1005-1011.

  [2]. Do TQ, et al. Lipids including cholesteryl linoleate and cholesteryl arachidonate contribute to the inherent antibacterial activity of human nasal fluid. J Immunol. 2008;181(6):4177-4187.

  [3]. Vahouny GV, et al. Cholesterol arachidonate as a prostaglandin precursor in adrenocortical cells. Prostaglandins. 1978;16(2):207-220.