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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0946S
    Sulfamonomethoxine-d4
    99.90%
    Sulfamonomethoxine-d4 is a deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity.
    Sulfamonomethoxine-d<sub>4</sub>
  • HY-143915S
    Amitriptyline-N-glucuronide-d3
    Amitriptyline-N-glucuronide-d3 is the deuterium labeled Amitriptyline-N-glucuronide.
    Amitriptyline-N-glucuronide-d<sub>3</sub>
  • HY-N2145S
    4',7-Dimethoxyisoflavone-d6
    98.82%
    4',7-Dimethoxyisoflavone-d6 (Dimethoxydaidzein-d6) is the deuterium labeled 4',7-Dimethoxyisoflavone (HY-N2145). 4',7-Dimethoxyisoflavone is isolated from the leaves of Albizzia lebbeck, which shows antifungal activity.
    4',7-Dimethoxyisoflavone-d<sub>6</sub>
  • HY-119649S
    Flonicamid-15N18O
    98.0%
    Flonicamid-15N,18O (IKI220-15N,18O) is 15N labeled Flonicamid. Flonicamid (IKI220) is a novel systemic insecticide with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues.
    Flonicamid-<sup>15</sup>N<sup>18</sup>O
  • HY-142786S
    Di-o-tolyl-phosphate-d14
    99.34%
    Di-o-tolyl-phosphate-d14 is the deuterium labeled Di-o-tolyl-phosphate.
    Di-o-tolyl-phosphate-d<sub>14</sub>
  • HY-Y0399S
    L-Norvaline-d5
    99.9%
    L-Norvaline-d5 is the deuterium labeled L-Norvaline. L-Norvaline is the inhibitor for arginase, that promotes the production of NO, reduces oxidative stress, improves insulin resistance, and exhibits antioxidant and anti-hyperglycemic effects. L-Norvaline can be used in research of Alzheimer’s disease.
    L-Norvaline-d<sub>5</sub>
  • HY-B0261S4
    Meloxicam-13C6
    Meloxicam-13C6 is 13C6-labeled Meloxicam (HY-B0261). Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively.
    Meloxicam-<sup>13</sup>C<sub>6</sub>
  • HY-W749327
    2,4-Di-tert-butylphenol-d21
    2,4-Di-tert-butylphenol-d21 (2,4-DTBP-d21) is the deuterium labeled 2,4-Di-tert-butylphenol (HY-W014589). 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances.
    2,4-Di-tert-butylphenol-d<sub>21</sub>
  • HY-106339S
    Lymecycline-d8
    Lymecycline-d8 is the deuterium labeled Lymecycline.
    Lymecycline-d<sub>8</sub>
  • HY-14870S1
    Selexipag-d7
    98.44%
    Selexipag-d7 is the deuterium labeled Selexipag. Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor).
    Selexipag-d<sub>7</sub>
  • HY-Y1217S1
    1-Cyclohexanol-d11
    1-Cyclohexanol11 (Hydroxycyclohexane11; NSC 5471111) is the deuterium labeled 1-Cyclohexanol (HY-Y1217). 1-Cyclohexanol is an orally active Cramer Class I flavor ingredient that can be used in fragrances. 1-Cyclohexanol has a wide margin of safety and is environmentally friendly.
    1-Cyclohexanol-d<sub>11</sub>
  • HY-W017443S1
    L-Asparagine-amide-15N monohydrate
    99.80%
    L-Asparagine-amide-15N monohydrate is the 15N-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
    L-Asparagine-amide-<sup>15</sup>N monohydrate
  • HY-N1480S
    (-)-Fucose-13C
    99.86%
    (-)-Fucose-13C is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti
    (-)-Fucose-<sup>13</sup>C
  • HY-W035399S
    D-Lysine-d8 dihydrochloride
    99.9%
    D-Lysine-d8 (dihydrochloride) is the deuterium labeled D-Lysine.
    D-Lysine-d<sub>8</sub> dihydrochloride
  • HY-N0830BS
    Palmitic acid-13C sodium
    98.0%
    Palmitic acid-13C (sodium) is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.
    Palmitic acid-<sup>13</sup>C sodium
  • HY-W015267S
    2-Chlorobiphenyl-2′,3′,4′,5′,6′-d5
    99.7%
    2-Chlorobiphenyl-2′,3′,4′,5′,6′-d5 is the deuterium labeled 2-Chlorobiphenyl.
    2-Chlorobiphenyl-2′,3′,4′,5′,6′-d<sub>5</sub>
  • HY-144031S
    Tyk2-IN-8
    98.04%
    Tyk2-IN-8 (compound 3) is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3.0 nM. Tyk2-IN-8 can be used for the research of autoimmune disease.
    Tyk2-IN-8
  • HY-156985
    Lipid AX4
    98.5%
    Lipid AX4 is an ionizable cationic lipid with the pKa of 6.89, and can be used the study for the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.
    Lipid AX4
  • HY-150779S
    Choline-d13 sulfate
    98.3%
    Choline-d13 (sulfate) is the deuterium labeled Choline sulfate.
    Choline-d<sub>13</sub> sulfate
  • HY-N8440S1
    Gibberellin A4-d2
    Gibberellin A4-d2 is the deuterium labeled Gibberellin A4 (HY-N8440).
    Gibberellin A4-d2