Acetyl hexapeptide-1 (Synonyms: Melitane)

Cat. No.: HY-P5220 Purity: 99.43%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Acetyl hexapeptide-1 (Melitane) is a biomimetic peptide that mimics the activity of α-melanocyte-stimulating hormone (α-MSH). Acetyl hexapeptide-1 regulates muscle contraction, thereby reducing facial expression lines. Acetyl hexapeptide-1 is one of the components of anti-aging skincare serums targeting dynamic wrinkles. Acetyl hexapeptide-1 can be used in research related to mild photoaged facial skin and premature gray hair.

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Acetyl hexapeptide-1 화학구조

CAS No. : 448944-47-6

사이즈	재고	수량
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	견적 받기
200 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

Other Forms of Acetyl hexapeptide-1:

Acetyl hexapeptide-1 acetate In-stock

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•Related Screening Libraries:

•Related Small Molecules:

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View All Melanocortin Receptor Isoform Specific Products:

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MC1R MC3R MC2R MC4R MC5R

Biological Activity
순도&문서
References
고객리뷰

제품 설명

In Vitro

Acetyl hexapeptide-1 acts directly on melanocytes in hair follicles to promote hair repigmentation. In skin care products, it is used to induce healthy skin pigmentation, helping to improve uneven skin tone and local paleness. Acetyl hexapeptide-1 also reduces skin erythema and inflammatory responses, and helps repair UV-induced DNA damage, making the skin appear healthier^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

870.01

화학식

C₄₃H₅₉N₁₃O₇

CAS No.

448944-47-6

Appearance

Solid

Color

White to off-white

Sequence

Ac-{Nle}-Ala-His-{d-Phe}-Arg-Trp-NH2

Sequence Shortening

Ac-{Nle}-AH-{d-Phe}-RW-NH2

선적

Room temperature in continental US; may vary elsewhere.

보관

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

H₂O : 25 mg/mL (28.74 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1494 mL	5.7471 mL	11.4941 mL
5 mM	0.2299 mL	1.1494 mL	2.2988 mL
10 mM	0.1149 mL	0.5747 mL	1.1494 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.43%

Select Batch:

Data Sheet (275 KB) SDS (254 KB)

COA (252 KB) RP-HPLC (109 KB) MS (257 KB)

Handling Instructions (2659 KB)

References

[1]. Ye Y, et al. Improvement of mild photoaged facial skin in middle-aged Chinese females by a supramolecular retinol plus acetyl hexapeptide-1 containing essence. Skin Health Dis. 2023;3(4):e239. Published 2023 May 7. [Content Brief]

[2]. Sehrawat M, et al. Biology of hair pigmentation and its role in premature canities. Pigment International. 2017 Jan 1;4(1):7-12.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.1494 mL	5.7471 mL	11.4941 mL	28.7353 mL
	5 mM	0.2299 mL	1.1494 mL	2.2988 mL	5.7471 mL
	10 mM	0.1149 mL	0.5747 mL	1.1494 mL	2.8735 mL
	15 mM	0.0766 mL	0.3831 mL	0.7663 mL	1.9157 mL
	20 mM	0.0575 mL	0.2874 mL	0.5747 mL	1.4368 mL
	25 mM	0.0460 mL	0.2299 mL	0.4598 mL	1.1494 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Acetyl hexapeptide-1 Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Acetyl hexapeptide-1448944-47-6MelitaneAcetyl hexapeptide1Acetyl hexapeptide 1Melanocortin ReceptorMC Receptormild photoaged facial skinpremature canitiesfacial expression linesdynamic wrinklesmuscle contractionInhibitorinhibitorinhibit

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