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  4. Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC

Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC  (Synonyms: Salmiac, meets analytical specification of Ph. Eur. BP USP FCC)

製品番号: HY-Y1269H
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Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC (Salmiac, meets analytical specification of Ph. Eur. BP USP FCC) can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor.

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CAS 番号 : 12125-02-9

容量 在庫状況
50 mg   お問い合わせ  
100 mg   お問い合わせ  
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    Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 4:e04680.  [Abstract]

    Resistant cells were treated with 25 mM Ammonium chloride (NH4Cl) alone or co‐treated with 80 µm FA, and the expression level of DDX6 was detected by immunoblotting, n = 3. The results showed that supplementation with the lysosomal inhibitor NH4Cl could rescue DDX6 expression reduced by FA intervention.

    Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC purchased from MedChemExpress. Usage Cited in: MedComm (2020). 2025 Aug 31;6(9):e70353.  [Abstract]

    HEK293T‐hACE2 cells were exposed to pseudotyped SARS‐COV‐2 (wild type and two variants: B.1.351 and B.1.671) or VSV (MOI = 10) in the presence of varying concentrations of tetrandrine or Ammonium chloride (NH4Cl). Firefly luciferase activity, indicative of infection, was measured 24 h post‐infection and normalized to the mock‐treated control. *p < 0.05, **p < 0.01, ***p < 0.001 versus virus control. Mock, cell group. Con, virus‐infected group.

    Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC purchased from MedChemExpress. Usage Cited in: Cancer Lett. 2025 Apr 10:217715.  [Abstract]

    Western blot was used to test the influence of Bufalin (100 nM) combined with Ammonium chloride (NH4CL, 30 mM) or BafA1 (50 nM) for different time (0, 0.5, 1, 2 h) in KYSE30 and KYSE450. The results showed that Bufalin-induced EGFR degradation could be reversed by lysosomal protease NH4CL.

    Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC purchased from MedChemExpress. Usage Cited in: Eur J Med Chem. 2025 Jun 14:296:117871.  [Abstract]

    Immunoblots and quantification of EGFR in A549 cells treated with different concentrations of LY-dE#5, with or without MG132, CQ, and Ammonium chloride (NH4Cl) (0.5-2 μM). The results showed that NH4Cl significantly blocked LY-dE#5-mediated EGFR degradation.

    Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC purchased from MedChemExpress. Usage Cited in: PLoS Pathog. 2025 Jul 16;21(7):e1013344.  [Abstract]

    293T cells were transfected with the pCAGGS-HA-ORF3a plasmid and subsequently treated with Ammonium chloride (NH4Cl) (20 mM). Cells were harvested after 48 h, and the expression levels of endogenous YY1 were assessed by Western blot using either HA or YY1 antibodies.

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    製品説明

    Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC (Salmiac, meets analytical specification of Ph. Eur. BP USP FCC) can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor[1][2][3].

    臨床実験
    分子量

    53.49

    分子式

    ClH4N
    CAS 番号
    SMILES

    N.Cl
    輸送条件

    Room temperature in continental US; may vary elsewhere.
    保管条件

    Please store the product under the recommended conditions in the Certificate of Analysis.
    純度とドキュメンテーション
    参考文献
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    Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC Related Classifications

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    Keywords:

    Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC12125-02-9Salmiac, meets analytical specification of Ph. Eur. BP USP FCCAutophagyBiochemical Assay ReagentsAutophagy InhibitorInhibitorinhibitorinhibit

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