Copy Link Print Information

Ammonium chloride, for molecular biology

(Synonyms: Salmiac, for molecular biology)
62 Cited Publications
Customer Review

Based on 62 publication(s) in Google Scholar

Ammonium chloride (Salmiac), for molecular biology is an inhibitor of Slc26a4 and SMAD2. Ammonium chloride, for molecular biology reduces the protein expression level of Slc26a4 in lung tissue, and attenuates ozone-induced increases in proinflammatory cytokines, inflammatory cells, pulmonary resistance, goblet cell hyperplasia, peribronchial inflammation and thiocyanate levels in mouse tissues and bronchoalveolar lavage fluid. Ammonium chloride, for molecular biology decreases the level of phosphorylated SMAD2, inhibits autophagy by reducing autophagy-related proteins, and enhances Cisplatin (HY-17394)-induced cancer cell apoptosis and DNA double-strand breaks. Ammonium chloride, for molecular biology also inhibits the TCA cycle, reduces ATP production, increases glucose utilization, regulates the levels of lactic acid, glutamic acid and ATP, and induces morphological degeneration of neuroblastoma cells. Ammonium chloride, for molecular biology can be used in studies related to ozone-induced airway injury, hepatocellular carcinoma, human cervical cancer, hepatic encephalopathy, Reye syndrome, epilepsy and neurodegenerative diseases.

For research use only. We do not sell to patients.

  • CAS No.: 12125-02-9
  • Formula: NH4Cl
  • Molecular Weight:53.49
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Ammonium chloride, for molecular biology Chemical Structure
    Ammonium chloride, for molecular biology Chemical Structure
  • Experimental Validation Results for Ammonium chloride, for molecular biology
  • Experimental Validation Results for Ammonium chloride, for molecular biology
  • Experimental Validation Results for Ammonium chloride, for molecular biology
  • Experimental Validation Results for Ammonium chloride, for molecular biology
  • Experimental Validation Results for Ammonium chloride, for molecular biology
CAS No.: 12125-02-9
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Ammonium chloride, for molecular biology:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Purity & Documentation
  • References
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Ammonium chloride, for molecular biology

More
Customer Validation & Images
WBBio/Physico-chemical Assay
  • WB
  • Bio/Physico-chemical Assay
  • WB
  • WB
  • WB

All TGF-beta/Smad Isoforms

More

Keywords

MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Ammonium chloride, for molecular biology Chemical Structure
    Ammonium chloride, for molecular biology Chemical Structure
    1/16
  • 1/16

    Ammonium chloride, for molecular biology purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 4:e04680. [Abstract]

    Customer Validation
     Resistant cells were treated with 25 mM Ammonium chloride (NH4Cl) alone or co‐treated with 80 µm FA, and the expression level of DDX6 was detected by immunoblotting, n = 3. The results showed that supplementation with the lysosomal inhibitor NH4Cl could rescue DDX6 expression reduced by FA intervention.

  • 1/16

    Ammonium chloride, for molecular biology purchased from MedChemExpress. Usage Cited in: MedComm (2020). 2025 Aug 31;6(9):e70353. [Abstract]

    Customer Validation
     HEK293T‐hACE2 cells were exposed to pseudotyped SARS‐COV‐2 (wild type and two variants: B.1.351 and B.1.671) or VSV (MOI = 10) in the presence of varying concentrations of tetrandrine or Ammonium chloride (NH4Cl). Firefly luciferase activity, indicative of infection, was measured 24 h post‐infection and normalized to the mock‐treated control. *p < 0.05, **p < 0.01, ***p < 0.001 versus virus control. Mock, cell group. Con, virus‐infected group.

  • 1/16

    Ammonium chloride, for molecular biology purchased from MedChemExpress. Usage Cited in: Cancer Lett. 2025 Jul 28:623:217715. [Abstract]

    Customer Validation
     Western blot was used to test the influence of Bufalin (100 nM) combined with Ammonium chloride (NH4CL, 30 mM) or BafA1 (50 nM) for different time (0, 0.5, 1, 2 h) in KYSE30 and KYSE450. The results showed that Bufalin-induced EGFR degradation could be reversed by lysosomal protease NH4CL.

  • 1/16

    Ammonium chloride, for molecular biology purchased from MedChemExpress. Usage Cited in: Eur J Med Chem. 2025 Oct 15:296:117871. [Abstract]

    Customer Validation
     Immunoblots and quantification of EGFR in A549 cells treated with different concentrations of LY-dE#5, with or without MG132, CQ, and Ammonium chloride (NH4Cl) (0.5-2 μM). The results showed that NH4Cl significantly blocked LY-dE#5-mediated EGFR degradation.

  • 1/16

    Ammonium chloride, for molecular biology purchased from MedChemExpress. Usage Cited in: PLoS Pathog. 2025 Jul 16;21(7):e1013344. [Abstract]

    Customer Validation
     293T cells were transfected with the pCAGGS-HA-ORF3a plasmid and subsequently treated with Ammonium chloride (NH4Cl) (20 mM). Cells were harvested after 48 h, and the expression levels of endogenous YY1 were assessed by Western blot using either HA or YY1 antibodies.

  • Ammonium chloride, for molecular biology