Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2)

Name: Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2)
Brand: MedChemExpress
SKU: HY-P99145
Rating: 5.0 (15 reviews)

製品番号: HY-P99145 純度: 99.68%: Data Sheet SDS COA
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Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) is an anti-mouse PD-L1/B7-H1 IgG2b antibody inhibitor derived from host rat. Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) blocks PD-1 signaling. Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) can be used for the research of cancer, such as colon cancer.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量	価格（税別）	在庫状況	数量
>無料サンプル (100 μg)		今すぐ申し込む
>無料サンプル (100 μg)		今すぐ申し込む
1 mg	$85	在庫あり	Estimated Time of Arrival: December 31
5 mg	$290	在庫あり	Estimated Time of Arrival: December 31
10 mg	$465	在庫あり	Estimated Time of Arrival: December 31
25 mg	$860	在庫あり	Estimated Time of Arrival: December 31
50 mg	$1350	在庫あり	Estimated Time of Arrival: December 31
100 mg	$2150	在庫あり	Estimated Time of Arrival: December 31
200 mg		お問い合わせ
500 mg		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

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Based on 15 publication(s) in Google Scholar

Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) Featured Recommendations:

顧客検証

In Vivo Imaging

In Vivo Efficacy Study

: Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Aug 28;16(1):8054. [Abstract]; In vivo NIR-II fluorescence images, ratio plots and the corresponding ratio signal (F_{1060 nm}/F_{1525 nm}) values at the tumor site on day 10 after anti-PD-L1 antibody (Anti-Mouse PD-L1/B7-H1 Antibody, 100 μg in 100 μL PBS; i.p.; every three days for a total of three doses) treatment in tumor-bearing mice.

: Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Dec 5;16(1):10880. [Abstract]; NIR-IIb fluorescence ratiometric imaging and NIR-IIb fluorescence quantification/ratiometric analysis of different groups. In the immunotherapy group, the mice received intraperitoneal injection of anti-PD-L1 antibody (Anti-Mouse PD-L1/B7-H1 Antibody) on alternate days. On day 7, the mice received intravenous injection with Bi-HCy-ErNPs (n = 6).

: Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Apr;12(15):e2412109. [Abstract]; Tumor size, tumor growth curves, and tumor volume of C57BL/6 mice injected subcutaneously with U14 cells (n = 4). The results showed that anti-mouse PD-L1/B7-H1 antibody (αPD-L1, 3 mg/kg; i.p.; twice a week) monotherapy significantly slowed tumor growth, whereas combination therapy with FK866 (20 mg/kg; i.p.; twice a week) and αPD-L1 achieved the strongest tumor suppressive effect.

: Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Jan 28;23(1):48. [Abstract]; Fluorescence microscopy observations of aPDL1-DTX/PFP@Lipid binding to Pan02 cells. Red fluorescence indicates NPs labeled with DiI (scale bar = 25 μm). The results showed that the binding of nanoparticles was reduced in the presence of free aPD-L1 antibody (Anti-Mouse PD-L1/B7-H1 Antibody).

: Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) purchased from MedChemExpress. Usage Cited in: J Control Release. 2025 Sep 10:385:113998. [Abstract]; Photographs of tumors from the same treatment groups and changes in tumor volume during treatment. antiPD-L1 antibody (Anti-Mouse PD-L1/B7-H1 Antibody, 100 μg/mouse; administered every two days for three doses).

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製品説明

Isotype

Rat IgG2b kappa

Recommend Isotype Controls

Rat IgG2b kappa, Isotype Control

Species Reactivity

Mouse

IC₅₀ & Target

PD-L1/B7-H1

体内実験

Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) (0.8 mg/kg, ip, every 2 days for 3 doses) exhibits antitumor efficacy against primary tumor and metastatic tumor in CT26 xenograft mouse models^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	CT26 xenograft mouse models^[1]
Dosage:	0.8 mg/kg
Administration:	Intraperitoneally injection, every 2 days for 3 doses
Result:	Inhibited the tumor growth, prolonged the mouse survival rate.

Gene ID

60533 [NCBI]

Accession

Q9EP73

Application

in vivo PD-L1 blockade; in vitro PD-L1 blockade; Immunofluorescence; Immunohistochemistry (frozen

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

分子量

150 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2)]

輸送条件

Shipping with dry ice.

Formulation

Please refer to the lot-specific COA for specific buffer information.

保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

Biological Activity

Immobilized PD-L1 Protein, Mouse (HEK293, His, HY-P70632) can bind Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2). The EC₅₀ for this effect is 9.78 ng/mL.
Flow cytometric analysis of 1X10⁶ MC38 cells with Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) (HY-P99145, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rat IgG H&L (HY-P89199) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Rat IgG2a kappa (HY-P990679, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

純度とドキュメンテーション

純度: 99.68%

Select Batch:

データシート (260 KB) SDS (251 KB)

COA (232 KB) SDS-PAGE (69 KB) SEC-HPLC (70 KB)

Inhibitory Antibodies User Guide (603 KB)

参考文献

[1]. Wang Y, et al. Mesoporous dual-atom nanozyme induced cuproptosis and apoptosis for boosting immunogenic cell death along with reprogramming tumor immune-suppressive microenvironment[J]. Chemical Engineering Journal, 2025: 160294.

Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量		濃度		体積		分子量 *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）	×	体積 _（開始）	=	濃度 _（終了）	×	体積 _（終了）
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2)PD-1/PD-L1PD-1/Programmed death-ligand 1PD-L1B7-H1PD-1CancerCT26Inhibitorinhibitorinhibit

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Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2)

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•関連スクリーニングライブラリ:

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生物活性

純度とドキュメンテーション

参考文献

カスタマーレビュー

Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) Related Classifications

Molarity Calculator

Dilution Calculator

The molarity calculator equation

The dilution calculator equation

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