2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. CD68 Antibody (YA799)

CD68 Antibody (YA799) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD68.

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Top Publications Citing Use of Products

1 Publications Citing Use of MCE CD68 Antibody (YA799)

  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Descripciòn

  • Referencias

Descripciòn

CD68 Antibody (YA799) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD68.
Host

Mouse
Clonality

Monoclonal
Peso molecular
Predicted band size: 37 kDa;
Observed band size: 37 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Gene ID
Immunogen

Synthetic peptide corresponding to CD68.The exact sequence is proprietary to MCE.
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:100
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:50-1:200
Sensitivity Endogenous Pureza affinity purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG1  
Appearance

Liquid
Formulation

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Envío

Shipping with blue ice.
Background
Function：Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells
Subcellular Localization：Cell membrane; Single-pass type I membrane protein; Endosome membrane; Single-pass type I membrane protein; Lysosome membrane; Single-pass type I membrane protein
Expression：
Tissue_specificity:It is highly expressed in blood monocytes and tissue macrophages. It is also expressed in lymphocytes, fibroblasts, and endothelial cells. It is expressed in many tumor cell lines, which may enable them to attach to selectins on vascular endothelium, thereby promoting their spread to secondary sites.
Isoforms & Post-Translational Modification：P34810 has 3 isomers: P34810-1: 37408 Da (predicted); P34810-2: 31738 Da (predicted); P34810-3: 34654 Da (predicted).
N- and O-glycosylated
RRID
Database

Entrez Gene: 968 Human

SwissProt: P34810 Human

OMIM: 153634 Human

Research Field

Immunology
Synonyms
CD68; Macrosialin; Gp110; CD68
Documentación
SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)
Referencias

CD68 Antibody (YA799) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
CD68 Antibody (YA799)
Cat. No.:
HY-P80605
Cantidad:
MCE Japan Authorized Agent:

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Observaciones

SAFETY DATA SHEET (SDS)

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