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  3. AP-1/NF-κB activation inhibitor 1

AP-1/NF-κB activation inhibitor 1 

Cat. No.: HY-133987
Handling Instructions

AP-1/NF-κB activation inhibitor 1 is a potent AP-1 and NF-κB mediated transcriptional activation inhibitor (IC50=1 μM), without blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells.

For research use only. We do not sell to patients.

AP-1/NF-κB activation inhibitor 1 Chemical Structure

AP-1/NF-κB activation inhibitor 1 Chemical Structure

CAS No. : 188936-12-1

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Description

AP-1/NF-κB activation inhibitor 1 is a potent AP-1 and NF-κB mediated transcriptional activation inhibitor (IC50=1 μM), without blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells[1].

Molecular Weight

344.25

Formula

C₁₃H₁₁F₃N₄O₄

CAS No.

188936-12-1

SMILES

O=C(C1=CN=C(C(F)(F)F)N=C1NN2C(C(C)=CC2=O)=O)OCC

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

AP-1/NF-κB activation inhibitor 1NF-κBNuclear factor-κBNuclear factor-kappaBtranscriptionalactivationstimulatedIL-2IL-8Inhibitorinhibitorinhibit

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AP-1/NF-κB activation inhibitor 1
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HY-133987
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