2. Metabolic Enzyme/Protease
  3. Aminotransferases (Transaminases)
  4. Aspartate aminotransferase, Human liver

Aspartate aminotransferase, Human liver  (Synonyms: EC 2.6.1.1, Human liver; GOT, Human liver; AST, Human liver)

製品番号: HY-P3016B
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Aspartate aminotransferase (EC 2.6.1.1), Human liver is a metabolic regulator with the highest activity in the heart, liver and skeletal muscle. Aspartate aminotransferase, Human liver comprises two isozymes: the cytoplasmic form (AST1) and the mitochondrial form (AST2). By catalyzing reversible transamination reactions between oxaloacetate, L-glutamate and other substances, it is deeply involved in key physiological processes such as amino acid metabolism, the tricarboxylic acid cycle and neurotransmitter synthesis. Aspartate aminotransferase, Human liver also provides substrate support for the synthesis of urea and purines/pyrimidines. Aspartate aminotransferase, Human liver is a serum marker reflecting cardiac and hepatic injury, and its abnormal levels are also closely associated with myocardial infarction, cardiovascular diseases and various cancers.

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Aspartate aminotransferase, Human liver

Aspartate aminotransferase, Human liver 構造式

CAS 番号 : 9000-97-9

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Aspartate aminotransferase, Human liver 関連抗体

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製品説明

Aspartate aminotransferase (EC 2.6.1.1), Human liver is a metabolic regulator with the highest activity in the heart, liver and skeletal muscle. Aspartate aminotransferase, Human liver comprises two isozymes: the cytoplasmic form (AST1) and the mitochondrial form (AST2). By catalyzing reversible transamination reactions between oxaloacetate, L-glutamate and other substances, it is deeply involved in key physiological processes such as amino acid metabolism, the tricarboxylic acid cycle and neurotransmitter synthesis. Aspartate aminotransferase, Human liver also provides substrate support for the synthesis of urea and purines/pyrimidines. Aspartate aminotransferase, Human liver is a serum marker reflecting cardiac and hepatic injury, and its abnormal levels are also closely associated with myocardial infarction, cardiovascular diseases and various cancers[1][2][3].

体外実験

Aspartate aminotransferase, Human liver has increased synthesis and release in adipocytes treated with rosiglitazone (HY-17386), which catalyzes the aminotransferase reaction between aspartate and α-ketoglutarate[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aspartate aminotransferase, Human liver 関連抗体
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[Aspartate aminotransferase, Human liver]
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保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.
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Keywords:

Aspartate aminotransferase, Human liver9000-97-9EC 2.6.1.1, Human liver GOT, Human liver AST, Human liverAminotransferases (Transaminases)IRE1α/c-Jun signaling pathwayisoniazidAST1maleateadipocytesAspartate aminotransferaseHuman liverAST2aminooxyacetateHepG2 hepatoma cellssuccinateInhibitorinhibitorinhibit

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