Aspartate aminotransferase, Genetically engineered bacteria
Based on 1 publication(s) in Google Scholar
Aspartate aminotransferase (EC 2.6.1.1), Genetically engineered bacteria is a metabolic regulator with the highest activity in the heart, liver and skeletal muscle. Aspartate aminotransferase, Genetically engineered bacteria comprises two isozymes: the cytoplasmic form (AST1) and the mitochondrial form (AST2). By catalyzing reversible transamination reactions between oxaloacetate, L-glutamate and other substances, it is deeply involved in key physiological processes such as amino acid metabolism, the tricarboxylic acid cycle and neurotransmitter synthesis. Aspartate aminotransferase, Genetically engineered bacteria also provides substrate support for the synthesis of urea and purines/pyrimidines. Aspartate aminotransferase, Genetically engineered bacteria is a serum marker reflecting cardiac and hepatic injury, and its abnormal levels are also closely associated with myocardial infarction, cardiovascular diseases and various cancers.
For research use only. We do not sell to patients.
- CAS No.: 9000-97-9
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Aspartate aminotransferase, Genetically engineered bacteria
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Biological Activity
Aspartate aminotransferase, Genetically engineered bacteria has increased synthesis and release in adipocytes treated with rosiglitazone (HY-17386), which catalyzes the aminotransferase reaction between aspartate and α-ketoglutarate[1].
This product can be used as a quality control product for ast kits and as an antigen to prepare anti-cAST antibodies.
Molecular weight: ~58kDa (SDS-PAGE)
pH Stability: 5.0-9.5 (20°C 24 h)
Thermal stability: no deactivation below 60°C for 30 min.
Reconstitution and dilution buffer: It is recommended to use phosphate buffer containing BSA.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
2.6.1.1
≥250 U/mL
Chemical Information
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CAS No. 9000-97-9
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Aspartate aminotransferase, Genetically engineered bacteria]
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Synonyms
EC 2.6.1.1; GOT; AST
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Metab
Hepatocyte-to-intestinal stem cell remote communication regulates blood glucose homeostasis. [Abstract]2026 Jul 7;38(7):1367-1384.e9. PMID: 42309059
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
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- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)