2. MAPK/ERK Pathway
  3. Raf
  4. BRAF V600E/CRAF-IN-1

BRAF V600E/CRAF-IN-1 (Compound 8b) is a potent inhibitor of BRAF V600E/CRAF. BRAF V600E/CRAF-IN-1 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-1 has the potential for the research of cancer diseases.

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BRAF V600E/CRAF-IN-1

BRAF V600E/CRAF-IN-1 Chemische Struktur

CAS. Nr. : 2499499-56-6

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BRAF V600E/CRAF-IN-1 Related Antibodies

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Beschreibung

BRAF V600E/CRAF-IN-1 (Compound 8b) is a potent inhibitor of BRAF V600E/CRAF. BRAF V600E/CRAF-IN-1 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-1 has the potential for the research of cancer diseases[1].

Molekulargewicht

505.41

Formel

C25H17F6N3O2
CAS. Nr.
SMILES

COC1=C2C=CC(NC3=CC(NC(C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=O)=CC=C3)=NC2=CC=C1
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Room temperature in continental US; may vary elsewhere.
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BRAF V600E/CRAF-IN-1 Related Classifications

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Keywords:

BRAF V600E/CRAF-IN-12499499-56-6RafRaf kinasesapoptosiscell cycle arrestG0/G1 phasecancerInhibitorinhibitorinhibit

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