2499499-56-6
Chemical Structure
BRAF V600E/CRAF-IN-1
- CAS No.: 2499499-56-6
- Formula:C25H17F6N3O2
- Molecular Weight:505.41
IUPAC Name: N-(3-((5-methoxyquinolin-2-yl)amino)phenyl)-3,5-bis(trifluoromethyl)benzamide
InChIKey: ZOFPYTOXNJKYQJ-UHFFFAOYSA-N
SMILES: COC1=C2C=CC(NC3=CC(NC(C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=O)=CC=C3)=NC2=CC=C1
Biological Activity: BRAF V600E/CRAF-IN-1 (Compound 8b) is a potent inhibitor of BRAF V600E/CRAF. BRAF V600E/CRAF-IN-1 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-1 has the potential for the research of cancer diseases[1].
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BRAF V600E/CRAF-IN-1 | BRAF V600E/CRAF-IN-1 (Compound 8b) is a potent inhibitor of BRAF V600E/CRAF. BRAF V600E/CRAF-IN-1 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-1 has the potential for the research of cancer diseases. | |||||||||||||||||||||
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Keywords