2499499-56-6

BRAF V600E/CRAF-IN-1 Chemical Structure
2499499-56-6

Chemical Structure

BRAF V600E/CRAF-IN-1

  • CAS No.: 2499499-56-6
  • Formula:C25H17F6N3O2
  • Molecular Weight:505.41

IUPAC Name: N-(3-((5-methoxyquinolin-2-yl)amino)phenyl)-3,5-bis(trifluoromethyl)benzamide

InChIKey: ZOFPYTOXNJKYQJ-UHFFFAOYSA-N

SMILES: COC1=C2C=CC(NC3=CC(NC(C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=O)=CC=C3)=NC2=CC=C1

Biological Activity: BRAF V600E/CRAF-IN-1 (Compound 8b) is a potent inhibitor of BRAF V600E/CRAF. BRAF V600E/CRAF-IN-1 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-1 has the potential for the research of cancer diseases[1].

Cat. No. Product Name Purity Description Pricing
HY-146442
BRAF V600E/CRAF-IN-1 BRAF V600E/CRAF-IN-1 (Compound 8b) is a potent inhibitor of BRAF V600E/CRAF. BRAF V600E/CRAF-IN-1 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-1 has the potential for the research of cancer diseases.
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