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  4. Calcium disodium edetate hydrate

Calcium disodium edetate hydrate  (Synonyms: EDTA (disodium calcium salt hydrate); Ethylenediaminetetraacetic acid (disodium calcium salt hydrate); エチレンジアミン四酢酸 カルシウム二ナトリウム 水和物)

製品番号: HY-W250119 純度: 98.0%
COA 取扱説明書 Technical Support

Calcium disodium edetate hydrate (EDTA disodium calcium salt hydrate) is a metal chelator and antifungal agent. Calcium disodium edetate hydrate chelates Mn2+, damages mitochondria, and interferes with carbohydrate metabolic pathways, particularly the synthesis of pyruvate in glycolysis. Calcium disodium edetate hydrate inhibits Penicillium digitatum and delays conidial germination. Calcium disodium edetate (hydrate) enhances the host defense system of citrus fruits. Calcium disodium edetate hydrate is applicable to research related to citrus green mold.

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CAS 番号 : 23411-34-9

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100 mg $25 在庫あり
500 mg $50 在庫あり
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10 g $196 在庫あり
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Based on 24 publication(s) in Google Scholar

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Calcium disodium edetate hydrate 関連抗体

Top Publications Citing Use of Products

    Calcium disodium edetate hydrate purchased from MedChemExpress. Usage Cited in: Nat Immunol. 2025 Oct;26(10):1660-1672.  [Abstract]

    Representative images of CHMP4–GFP puncta (arrowheads; left) and percentage of CHMP4 speckle+ (top right) or Annexin V+ (bottom right) cells in BMDMs incubated with PBS, 15 µM SK56, 2 mM EDTA or EDTA + SK56 at 2 h after the addition of 1 μg/ml LPS + 10 μM nigericin; scale bar, 50 µm; n = 5 repeats

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    製品説明

    Calcium disodium edetate hydrate (EDTA disodium calcium salt hydrate) is a metal chelator and antifungal agent. Calcium disodium edetate hydrate chelates Mn2+, damages mitochondria, and interferes with carbohydrate metabolic pathways, particularly the synthesis of pyruvate in glycolysis. Calcium disodium edetate hydrate inhibits Penicillium digitatum and delays conidial germination. Calcium disodium edetate (hydrate) enhances the host defense system of citrus fruits. Calcium disodium edetate hydrate is applicable to research related to citrus green mold[1][2].

    体外実験

    Calcium disodium edetate hydrate (3.125-50 mmol L−1) completely inhibits hyphal growth of Penicillium digitatum strain P44 in vitro, with an MIC/MFC of 50 mmol L−1[2].
    Calcium disodium edetate hydrate (12.5-50 mmol L-1; 8-12 h) dose-dependently delays and inhibits conidial germination of Penicillium digitatum strain P44 in vitro[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Calcium disodium edetate hydrate 関連抗体
    体内実験

    Edetate calcium disodium hydrate (25-250 mmol L-1; intralesional injection) reduces the incidence of citrus green mold and decreases lesion size in a dose-dependent manner[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
    分子式

    C10H12CaN2O8.xH2O.2Na
    CAS 番号
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    O=C1[O-][Ca+2]([N]2(C1)CC3=O)([O-]3)([O-]C4=O)([O-]5)[N](C4)(CC2)CC5=O.[Na+].[x].[Na+].O
    輸送条件

    Room temperature in continental US; may vary elsewhere.
    保管条件

    4°C, sealed storage, away from moisture and light

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
    溶剤 & 溶解度
    体外: 

    H2O : ≥ 125 mg/mL

    *"≥" means soluble, but saturation unknown.

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    参考文献
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    Calcium disodium edetate hydrate Related Classifications

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    Keywords:

    Calcium disodium edetate23411-34-9EDTA disodium calcium saltEthylenediaminetetraacetic acid disodium calcium saltBiochemical Assay ReagentsFungalMitochondrial Metabolismlead poisoningcalciummagnesiummitochondriaironglycolytic pyruvate synthesisglomerular filtrationzincPenicillium digitatumcitrus green moldInhibitorinhibitorinhibit

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    製品名:
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    製品番号:
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