2. Immunology/Inflammation
  3. SphK
  4. CAY10621

CAY10621 (SKI 5C; compound 5c) is a specific sphingosine kinase 1 (SPHK1) inhibitor with an IC50 of 3.3 μM. CAY10621 is low toxic toward cells. CAY10621 has the potential for resistant cancer tumors research.

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CAY10621

CAY10621 Chemische Struktur

CAS. Nr. : 120005-55-2

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1 mg (22.95 mM * 100 μL in Methyl acetate) Auf Lager

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CAY10621 Related Antibodies

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Beschreibung

CAY10621 (SKI 5C; compound 5c) is a specific sphingosine kinase 1 (SPHK1) inhibitor with an IC50 of 3.3 μM. CAY10621 is low toxic toward cells. CAY10621 has the potential for resistant cancer tumors research[1].

IC50 & Target

SphK1

 

Cellular Effect
Cell Line Type Value Description References
CHO IC50
3.3 μM
Compound: 5c
Inhibition of EGFP-fused human SPHK1 expressed in CHO cells
Inhibition of EGFP-fused human SPHK1 expressed in CHO cells
[PMID: 19469544]
Molekulargewicht

435.64

Formel

C26H45NO4
CAS. Nr.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C(N1C(C)(C)OC[C@H]1C(C#CCCCCCCCCCCCCC)=O)OC(C)(C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Solution, -20°C, 2 years
Reinheit & Dokumentation

Purity: 99.3%

SDS (545 KB)

COA (243 KB)

Handling Instructions (2659 KB)
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CAY10621 Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CAY10621120005-55-2SKI 5CCAY 10621CAY-10621SphKSphingosine kinasesphingosine kinase 1SPHK1resistant cancer tumorsInhibitorinhibitorinhibit

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SAFETY DATA SHEET (SDS)

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